牙周组织力学加载模型的研究进展  

Research Progress on Mechanical Loading Model of Periodontium

作　　者：邓钰玮 蒋欣泉[1] 文晋 DENG Yuwei;JIANG Xinquan;WEN Jin(Department of Prosthodontics,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,College of Stomatology,Shanghai Jiao Tong University,National Center for Stomatology,National Clinical Research Centerfor Oral Diseases,Shanghai Key Laboratory of Stomatology,Shanghai Engineering Research Center of Advanced Dental Technology and Materials,Shanghai 200011,China)

机构地区：[1]上海交通大学医学院附属第九人民医院口腔修复科,上海交通大学口腔医学院,国家口腔医学中心,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,上海口腔医学先进技术与材料工程技术研究中心,上海200011

出　　处：《医用生物力学》2022年第3期562-567,共6页Journal of Medical Biomechanics

基　　金：国家自然科学基金项目(81900970);上海市青年科技英才扬帆计划(19YF1426000);上海交通大学医学院附属第九人民医院青年医师协同创新团队(QC202003)。

摘　　要：牙周组织具有机械力学响应性,可感受咀嚼力和正畸力在内的各种力学刺激并迅速产生反应,常作为力学加载对象在各种体内外模型相关的研究中广泛应用。本文回顾了近年来文献中对牙周组织的各种体内外力学加载方法(包括静态重力法、离心法、振动法、周期性张力法、流体剪应力法),对不同动物种属、加力方式及参数选择等进行梳理和总结,以期为研究牙周组织的力学响应机制以及开发、论证新的临床治疗技术提供参考。Periodontium is mechanoresponsive to multiple types of mechanical stimuli like occlusal and orthodontic force and reacts quickly.It is widely used as the loading subject in researches regarding dental mechanical force models both in vivo and in vitro.This review summarized various animal models and cell culture loading methods(including static gravity approach,centrifugation approach,vibration approach,cyclical tension approach,fluid flow approach),as well as parameters for periodontium in recent years,so as to provide references for the study of periodontal mechanoresponsive mechanism and the development of new clinical therapies.

关 键 词：牙周组织 力学响应机制 力学加载模型 

分 类 号：R318.01[医药卫生—生物医学工程]