儿童腺病毒肺炎免疫学发病机制研究进展  

Progress on immunological pathogenesis of adenovirus pneumonia in children

作　　者：赖小雪(综述) 邹映雪(审校)[1] Lai Xiaoxue;Zou Yingxue(Respiratory Department of Machang District,Tianjin Children′s Hospital(Children′s Hospital of Tianjin University),Tianjin 300134,China;Ganzhou Maternal and Child Health Hospital,Ganzhou 341000,China)

机构地区：[1]天津市儿童医院(天津大学儿童医院)马场院区呼吸科,300134 [2]赣州市妇幼保健院,341000

出　　处：《国际儿科学杂志》2022年第5期343-347,共5页International Journal of Pediatrics

基　　金：天津市自然科学基金重大项目(20JCZDJC00630)。

摘　　要：人腺病毒肺炎(简称腺病毒肺炎)是儿童社区获得性肺炎的重要类型之一。重症易发生于婴幼儿或免疫功能受损者,可导致急性肺损伤及肺部后遗症。严重感染时,炎症细胞和细胞因子反应的显著失衡引起组织损伤。该文就人腺病毒的分类、结构、感染受体及腺病毒肺炎的免疫学发病机制进行阐述。Human adenovirus pneumonia(adenovirus pneumonia for short)is one of the important types of community-acquired pneumonia in children.Severe pneumonia can easily occur in infants or patients with impaired immune function,which can lead to acute lung injury and pulmonary sequelae.In severe infection,the significant imbalance between inflammatory cells and cytokines leads to tissue damage.In this paper,the classification,structure,infection receptor of human adenovirus and the immunological pathogenesis of adenovirus pneumonia are described.

关 键 词：儿童 腺病毒肺炎 免疫学 发病机制 

分 类 号：R72[医药卫生—儿科]