采样延迟影响重症能量代谢测量精度的仿真研究  

Simulation Study on the Influence of Sampling Delay on the Accuracy of Energy Metabolism Measurement

作　　者：张安琪 陈焱焱[1] 王远[1] 方伟 孙怡宁[1] 马祖长[1] 杨先军[1] ZHANG Anqi;CHEN Yanyan;WANG Yuan;FANG Wei;SUN Yining;MA Zuchang;YANGXianjun(Hefei Institute of Physical Science,Chinese Academy of Sciences,Hefei,230031;University of Science and Technology of China,Hefei,230026)

机构地区：[1]中国科学院合肥物质科学研究院,合肥市230031 [2]中国科学技术大学,合肥市230026

出　　处：《中国医疗器械杂志》2022年第4期382-387,共6页Chinese Journal of Medical Instrumentation

基　　金：安徽省科技重大专项(18030801134,2020b07050001)。

摘　　要：间接能量代谢测量是提供重症营养支持的金标准,测量数据的准确性直接影响疾病的转归。为了研究采样延迟对机械通气下能量代谢测量精度的影响规律,使用Matlab/Simulink平台和呼吸系统电学模型进行仿真模拟和量化分析。结果表明,间接能量代谢测量误差随采样延时增加而增加,采样延时在机械通气模式下产生的误差比自主呼吸大,采样延时在机械通气PCV模式下产生的误差比VCV模式大。因此,在重症机械通气及其不同控制模式下应有不同的采样延时补偿策略。Indirect energy metabolism measurement is the gold standard for providing nutritional support for critical illness.The accuracy of the measurement data directly affects the outcome of the disease.In order to study the influence of sampling delay on the accuracy of energy metabolism measurement under mechanical ventilation,the Matlab/Simulink platform and respiratory electrical model were used for simulation and quantitative analysis.The results show that the error of indirect energy metabolism measurement increases with the increase of sampling delay,the error of sampling delay in mechanical ventilation mode is larger than that of spontaneous breathing,and the error of sampling delay in PCV mode of mechanical ventilation is larger than that in VCV mode.Therefore,there should be different sampling delay compensation strategies under severe mechanical ventilation and its different control modes.

关 键 词：间接能量代谢 逐次呼吸法 机械通气 旁流采样 采样延迟 

分 类 号：Q493.8[生物学—生理学]