肺弥散功能检测系统设计与验证  

Design and Verification of Lung Diffusion Function Detection System

作　　者：方伟 陈焱焱[1] 王远[1] 张安琪[1,2] 王沐 孙怡宁 马祖长[1] 杨先军[1] 徐玉兵[1] FANG Wei;CHEN Yanyan;WANG Yuan;ZHANG Anqi;WANG Mu;SUN Yining;MA Zuchang;YANG Xianjun;XU Yubing(Hefei Institutes of Physical Science,Chinese Academy of Sciences,Hefei,230031;University of Science and Technology of China,Hefei,230026)

机构地区：[1]中国科学院合肥物质科学研究院,合肥市230031 [2]中国科学技术大学,合肥市230026

出　　处：《中国医疗器械杂志》2022年第4期408-412,共5页Chinese Journal of Medical Instrumentation

基　　金：安徽省科技重大专项(18030801134,2020b07050001);安徽省重点研究与开发计划(S201904d08020031)。

摘　　要：设计一种肺弥散功能检测系统。首先,基于一口气法测量原理设计测试气路结构及其控制模块,实现空气、测试气源和标定气源的可控采集;然后,基于非分光红外传感器测量气体浓度、压差传感器测量气体流量、温湿度和大气压传感器获取测试环境参数,根据这些参数计算肺一氧化碳弥散量(D),实现肺弥散功能定量检测和评估。另外,还开展了肺弥散功能检测系统的初步验证,结果表明肺一氧化碳弥散量和肺泡容量误差均不超过5%。因此,该系统的准确性较高,对于慢阻肺的早期筛查和精准评估具有重要价值。A lung diffusion function detection system is designed.Firstly,the controllable collection of air,test gas source and calibration gas source was based on single-breath method measurement principle.Secondly,pulmonary diffusing capacity for carbon monoxide(Dl CO)was calculated by gas concentration measured by the non-dispersive infrared sensor to measure,the gas flow measured by the differential pressure sensor,and the temperature,humidity and atmospheric pressure sensors to test and evaluate the quantitative detection and evaluation of lung diffusion function.Moreover,a preliminary verification of the lung diffusion function detection system was implemented,and the results showed that the error of the lung carbon monoxide diffusion and the alveolar volume did not exceed 5%.Therefore,the system has high accuracy and is of great value for early screening and accurate assessment of COPD.

关 键 词：慢性阻塞性肺疾病 肺弥散功能检测 一氧化碳弥散量 

分 类 号：R197.39[医药卫生—卫生事业管理]