中国药物作用靶点研究新进展(Ⅰ)  

Progress of Research on Drug Targets in China(Ⅰ)

作　　者：江振洲[1,2] 范书生 刘家岐 俞沁玮 张陆勇 JIANG Zhenzhou;FAN Shusheng;LIU Jiaqi;YU Qinwei;ZHANG Luyong(Center for Drug Screening,China Pharmaceutical University,Nanjing 210009,China;Jiangsu Center for Pharmacodynamics Research and Evaluation,China Pharmaceutical University,Nanjing 210009,China;Center for Drug Research and Development,Guangdong Pharmaceutical University,Guangzhou 510006,China)

机构地区：[1]中国药科大学新药筛选中心,江苏南京210009 [2]中国药科大学江苏省药效研究与评价服务中心,江苏南京210009 [3]广东药科大学新药研发中心,广东广州510006

出　　处：《药学进展》2022年第6期471-480,I0005-I0018,共24页Progress in Pharmaceutical Sciences

摘　　要：通过检索2019—2020年中国学者在国内外杂志上发表的关于恶性肿瘤、心脑血管疾病、神经退行性疾病、精神障碍性疾病、自身免疫性疾病、感染性疾病、代谢类疾病等重大疾病治疗靶点的相关论文,分类综述这些重大疾病药物作用靶点研究的新进展,为创新药物的研发提供参考。Latest advances in the research on drug targets for a variety of major diseases, including tumors, cardiovascular and cerebrovascular diseases, neurodegenerative diseases, nerve disorders, autoimmune diseases, infectious diseases and metabolic diseases were investigated, based on the papers published in international and domestic journals by Chinese researchers in 2019-2020. New progress of research on drug targets of these major diseases has been summarized in this paper, aiming to provide reference and basis for the research and development of innovative drugs.

关 键 词：肿瘤 心脑血管疾病 神经退行性疾病 精神障碍性疾病 自身免疫性疾病 感染性疾病 代谢类疾病 药物治疗靶点 

分 类 号：R965[医药卫生—药理学]