慢性牙周炎与口腔幽门螺杆菌感染相关性分析  

Correlation between chronic periodontitis and oral Helicobacter pylori infection

作　　者：张敏[1] 高燕飞[1] 贾志宇 郭胜斌[1] ZHANG Min;GAO Yan-fei;JIA Zhi-yu;GUO Sheng-bin(Zhangjiakou University,Zhangjiakou,Hebei 075000,China;The Second Hospital of Hebei Medical University)

机构地区：[1]张家口学院,河北张家口075000 [2]河北医科大学第二医院

出　　处：《中国病原生物学杂志》2022年第6期706-709,共4页Journal of Pathogen Biology

摘　　要：目的 探讨慢性牙周炎与口腔幽门螺杆菌感染的相关性,为慢性牙周炎与幽门螺杆菌感染的预防提供研究依据。方法 根据CPI选取10颗指数牙,采用牙周探针检查牙周情况,将被确诊为慢性牙周炎的患者分为三级。采集龈下牙菌斑,采用快速尿素酶试剂与快速尿素酶试纸检测口腔幽门螺杆菌的感染情况。采用^(14)C-UBT,检测研究对象胃幽门螺杆菌的感染情况。使用SPSS 25.0软件统计分析病例的年龄、性别、BMI、CAL、PD、口腔幽门螺杆菌与胃幽门螺杆菌感染情况。结果 165例慢性牙周炎患者平均年龄37.02±6.82岁,其中女性76例(46.06%),男性89例(53.94%)。88例轻度慢性牙周炎患者,平均年龄34.84±6.67岁,52例中度慢性牙周炎患者平均年龄38.5±5.96岁,25例重度慢性牙周炎患者平均年龄41.88±5.89岁,不同组别年龄差异有统计学意义(P<0.05)。轻度慢性牙周炎患者男性47(53.41%)例,女性41例(46.59%),中度慢性牙周炎患者男性28例(53.85%),女性24例(46.15%),重度慢性牙周炎患者男性14例(56.00%),女性11例(44.00%),不同组别性别差异无统计学意义(P>0.05)。轻度慢性牙周炎患者中BMI≥28,7例(7.95%),中度慢性牙周炎患者中BMI≥28,11例(21.15%),重度慢性牙周炎患者中BMI≥28,9例(36.00%),不同组别BMI值差异有统计学意义(P<0.05)。轻度慢性牙周炎患者,PD平均(4.41±0.25)mm,中度慢性牙周炎患者,PD平均(6.01±0.71)mm,重度慢性牙周炎患者,PD平均(6.97±0.50)mm;轻度慢性牙周炎患者,CAL平均(3.47±0.27)mm,中度慢性牙周炎患者,CAL平均(5.19±0.50)mm,重度慢性牙周炎患者,CAL平均(6.68±0.32)mm。165例慢性牙周炎患者中,口腔Hp与胃Hp均阳性者59例(35.76%),单一口腔Hp阳性42例(25.45%),单一胃Hp阳性24例(14.55%)。80例牙周健康者中,口腔Hp与胃Hp均阳性者7例(8.75%),单一口腔Hp阳性12例(15.00%),单一胃Hp阳性7例(8.75%)。慢性牙周炎患者的口腔与胃幽门螺杆菌阳性率均大于牙Objective To explore the correlation between chronic periodontitis and oral H. pylori infection, and to provide research basis for the prevention of chronic periodontitis and H. pylori infection. Methods Ten index teeth were selected according to CPI,and the periodontal condition was examined by periodontal probe. The patients diagnosed with chronic periodontitis were divided into three levels. The subgingival plaque was collected and the oral H. pylori infection was detected by rapid urease reagent and rapid urease test paper.C-UBT was used to detect the infection of H. pylori in the stomach of the subjects. The age, sex, BMI,Cal, PD, oral H. pylori and gastric H. pylori infection of all cases were analyzed by SPSS 25.0 software. Results 165 patients with chronic periodontitis participated in this study, with an average age of 37.02±6.82 years, including 76 women(46.06%) and 89 men(53.94%). 88 patients with mild chronic periodontitis, with an average age of 34.84±6.67 years. 52 patients with moderate chronic periodontitis, with an average age of 38.5±5.96 years. 25 patients with severe chronic periodontitis, with an average age of 41.88±5.89 years. The difference of average age in different groups was statistically significant(P<0.05). There were 47 males(53.41%) and 41 females(46.59%) with mild chronic periodontitis. There were 28 males(53.85%) and 24 females(46.15%) with moderate chronic periodontitis. There were 14 males(56.00%) and 11 females(44.00%) with severe chronic periodontitis.There was no significant difference in the proportion of gender in different groups, P>0.05. Among patients with mild chronic periodontitis, BMI≥28,7 cases(7.95%). Among the patients with moderate chronic periodontitis, BMI≥28,11 cases(21.15%). There were 36 patients with moderate and severe periodontitis BMI≥28,9 cases(36.00%). There was significant difference in BMI between different groups(P<0.05). In patients with mild chronic periodontitis, the average PD was 4.41±0.25 mm. In patients with moderate chronic period

关 键 词：慢性牙周炎 幽门螺杆菌 相关性 

分 类 号：R378[医药卫生—病原生物学]