Negative self-feedback induced enhancement and transition of spiking activity for class-3 excitability  

作　　者：Li Li Zhiguo Zhao Huaguang Gu 黎丽;赵志国;古华光(Guangdong Key Laboratory of Modern Control Technology,Institute of Intelligent Manufacturing,Guangdong Academy of Sciences,Guangzhou 510070,China;School of Science,Henan Institute of Technology,Xinxiang 453003,China;School of Aerospace Engineering and Applied Mechanics,Tongji University,Shanghai 200092,China)

机构地区：[1]Guangdong Key Laboratory of Modern Control Technology,Institute of Intelligent Manufacturing,Guangdong Academy of Sciences,Guangzhou 510070,China [2]School of Science,Henan Institute of Technology,Xinxiang 453003,China [3]School of Aerospace Engineering and Applied Mechanics,Tongji University,Shanghai 200092,China

出　　处：《Chinese Physics B》2022年第7期203-213,共11页中国物理B（英文版）

基　　金：the National Natural Science Foundation of China(Grant Nos.11802085,11872276,and 12072236);the Science and Technology Project of Guangzhou(Grant No.202102021167);GDAS’Project of Science and Technology Development(Grant No.2021GDASYL20210103088);the Science and Technology Development Program of Henan Province,China(Grant No.212102310827)。

摘　　要：Post-inhibitory rebound(PIR)spike,which has been widely observed in diverse nervous systems with different physiological functions and simulated in theoretical models with class-2 excitability,presents a counterintuitive nonlinear phenomenon in that the inhibitory effect can facilitate neural firing behavior.In this study,a PIR spike induced by inhibitory stimulation from the resting state corresponding to class-3 excitability that is not related to bifurcation is simulated in the Morris–Lecar neuron.Additionally,the inhibitory self-feedback mediated by an autapse with time delay can evoke tonic/repetitive spiking from phasic/transient spiking.The dynamical mechanism for the PIR spike and the tonic/repetitive spiking is acquired with the phase plane analysis and the shape of the quasi-separatrix curve.The result extends the counterintuitive phenomenon induced by inhibition to class-3 excitability,which presents a potential function of inhibitory autapse and class-3 neuron in many neuronal systems such as the auditory system.

关 键 词：post-inhibitory rebound spike class 3 excitability inhibitory autapse neuronal firing 

分 类 号：TN911.7[电子电信—通信与信息系统] R318[电子电信—信息与通信工程]