对氟苯甲醛的合成研究  

Study on the Synthesis of p-Fluorobenzaldehyde

作　　者：马立强 张伟 MA Li-qiang;ZHANG Wei(Jiyuan Hengshun New Material Co.,Ltd.,Jiyuan 459000,China)

机构地区：[1]济源市恒顺新材料有限公司,河南济源459000

出　　处：《化学与粘合》2022年第4期321-323,358,共4页Chemistry and Adhesion

摘　　要：以对氟甲苯为原料,制备对氟苯甲醛。对氟甲苯在催化剂作用下经氯化、水解、精馏制备对氟苯甲醛。分析氯化反应、水解反应对对氟苯甲醛收率的影响。结果表明:(1)氯化反应时,通氯时间为3h,氯化反应温度为115℃时,对氟二氯苄含量较高;(2)水解反应时,水解温度控制在110~120℃,物质的量n∶n∶n=1∶1.6∶2.5时,得到产物的最高收率达到96%,对氟苯甲醛含量可达99%以上。该方法具有原料易得、反应条件简单、工艺稳定、反应总收率高的特点,并在工业生产中得到运用。The p-fluorobenzaldehyde is synthesized with p-fluorotoluene as a raw material by the process of chlorination, hydrolysis and distilla-tion of p-fluorotoluene under the action of a catalyst. The influence of chlorination reaction and hydrolysis reaction on the yield of p-fluorobenzalde-hyde is analyzed. The result shows that(1)During the chlorination reaction, the content of p-fluorodichlorobenzyl is higher when the time is 3h for adding chlorine and the chlorination reaction temperature is 115℃;(2) During the hydrolysis reaction, the highest yield of the obtained product can reach 96% and the content of p-fluorobenzaldehyde can reach more than 99% when the hydrolysis temperature is controlled in a range of 110 ~120℃and n: n: n= 1∶1.6∶2.5. This method has many characteristics such as convenient raw materials, simple reaction conditions, stable process and high total reaction yield, and it has been used in industrial production.

关 键 词：对氟甲苯 对氟苯甲醛 氯化 水解 

分 类 号：TQ245[化学工程—有机化工]