补肾活血汤加味对股骨近端骨折术后疼痛和睡眠效率的影响  

Effect of Modified Bushen Huoxue Tang on Pain and Sleep Efficiency in Patients After Surgery for Proximal Femur Fracture

作　　者：李鸿阁 宗慧凯 陈宝刚 LI Hongge;ZONG Huikai;CHEN Baogang

机构地区：[1]河南医学高等专科学校附属医院骨科,河南郑州451191

出　　处：《新中医》2022年第13期12-15,共4页New Chinese Medicine

摘　　要：目的:观察补肾活血汤加味对股骨近端骨折术后疼痛和睡眠效率的影响。方法:将120例股骨近端骨折术后患者随机分为结合组与对照组各60例。2组均行手术治疗,结合组术后服用补肾活血汤加味治疗。比较2组临床疗效、疼痛程度、睡眠质量及血清中碱性磷酸酶(ALP)、骨形态发生蛋白-2(BMP-2)、骨钙素(BGP)含量。结果:结合组总有效率96.67%,高于对照组83.33%(P<0.05)。与同组治疗前比较,治疗后1个月、3个月2组疼痛视觉模拟评分法(VAS)评分、睡眠质量均下降(P<0.05),血清ALP、BMP-2、BGP含量均升高(P<0.05);治疗后1个月、3个月,结合组VAS评分、睡眠质量均低于对照组(P<0.05),血清ALP、BMP-2、BGP含量均高于对照组(P<0.05)。结论:补肾活血汤加味治疗股骨近端骨折术后患者疗效显著,可降低疼痛程度,提高睡眠质量及血清中成骨生物活性指标的含量。Objective:To observe the effect of modified Bushen Huoxue tang on pain and sleep efficiency in patients after surgery for proximal femur fracture.Methods:A total of 120 cases of patients after surgery for proximal femur fracture were randomly divided into the combination group and the control group,with 60 cases in each group.Both groups were treated with surgery,and the combination group was treated with modified Bushen Huoxue tang after surgery.Clinical effects,pain degree,sleep quality and the contents of alkaline phosphatase(ALP),bone morphogenetic protein 2(BMP-2)and osteocalcin(BGP)in serum in the two groups were compared.Results:The total effective rate was 96.67%in the combination group,higher than that of 83.33%in the control group(P<0.05).One and three months after treatment,Visual Analogue Scale(VAS)scores of pain and sleep quality in the two groups were decreased when compared with those before treatment(P<0.05),and the contents of ALP,BMP-2 and BGP in serum were increased(P<0.05);VAS score and sleep quality in the combination group were lower than those in the control group(P<0.05),and the contents of ALP,BMP-2 and BGP in serum were higher(P<0.05).Conclusion:Modified Bushen Huoxue tang for patients after surgery for proximal femur fracture has a significant curative effect,which can reduce the pain degree,and improve the sleep quality and the contents of osteogenic bioactivity index in serum.

关 键 词：股骨近端骨折 补肾活血汤加味 疼痛 睡眠质量 成骨生物活性指标 

分 类 号：R274.1[医药卫生—中医骨伤科学]