蒲地蓝消炎口服液联合头孢呋辛钠治疗小儿急性化脓性扁桃体炎临床研究  

Clinical Study on Pudilan Xiaoyan Oral Liquid Combined with Cefuroxime Sodium for Acute Suppurative Tonsillitis in Children

作　　者：徐莎莎 傅佳佳 夏琴 XU Shasha;FU Jiajia;XIA Qin

机构地区：[1]绍兴第二医院医共体总院耳鼻咽喉科,浙江绍兴312000

出　　处：《新中医》2022年第13期116-119,共4页New Chinese Medicine

摘　　要：目的:观察蒲地蓝消炎口服液联合头孢呋辛钠治疗小儿急性化脓性扁桃体炎的疗效及对炎症的控制效果。方法:选取80例急性化脓性扁桃体炎患儿,按随机数字表法分为观察组与对照组各40例,对照组给予头孢呋辛钠加生理盐水静脉滴注,观察组在对照组基础上加用蒲地蓝消炎口服液,2组均治疗1周。比较2组临床疗效,比较2组治疗前后血清因子[白细胞计数(WBC)、血清C-反应蛋白(CRP)、降钙素原(PCT)]水平的变化,比较2组治疗后临床症状的消退时间。结果:观察组临床疗效总有效率为95.00%,对照组为80.00%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组WBC、CRP、PCT水平均较治疗前下降,观察组上述3项水平均低于对照组,差异均有统计学意义(P<0.05)。治疗后,观察组扁桃体肿大消退时间、脓性分泌物消退时间、咽痛消退时间、发热消退时间均短于对照组,差异均有统计学意义(P<0.05)。结论:蒲地蓝消炎口服液联合头孢呋辛治疗小儿急性化脓性扁桃体炎疗效显著,可降低血清炎症因子水平,控制炎症,促进化脓性扁桃体的消退。Objective:To observe the curative effect of Pudilan Xiaoyan oral liquid combined with cefuroxime sodium for acute suppurative tonsillitis in children and its control effect on inflammation.Methods:A total of 80 cases of children with acute suppurative tonsillitis were selected and divided into the observation group and the control group according to the random number table method,with 40 cases in each group.The control group was given intravenous infusion of cefuroxime sodium and normal saline,and the observation group was additionally given Pudilan Xiaoyan oral liquid based on the treatment of the control group.Both groups were treated for one week.The clinical effects in the two groups were compared;the changes in the levels of serum inflammatory factors including white blood cell count(WBC),serum C-reactive protein(CRP)and procalcitonin(PCT)before and after treatment in the two groups were compared;the regression time of clinical symptoms after treatment in the two groups was compared.Results:The total effective rate of clinical effect was 95.00%in the observation group and 80.00%in the control group,the difference being significant(P<0.05).After treatment,the levels of WBC,CRP and PCT in the two groups were decreased when compared with those before treatment,and the above three levels in the observation group were lower than those in the control group,differences being significant(P<0.05).After treatment,the regression time of antiadoncus,purulent secretion,pharyngalgia and fever in the observation group was shorter than that in the control group,differences being significant(P<0.05).Conclusion:The therapy of Pudilan Xiaoyan oral liquid combined with cefuroxime sodium for acute suppurative tonsillitis in children has a significant curative effect,and can reduce the levels of serum inflammatory factors,control inflammation and promote the regression of acute suppurative tonsillitis.

关 键 词：急性化脓性扁桃体炎 蒲地蓝消炎口服液 头孢呋辛钠 降钙素原 

分 类 号：R766.18[医药卫生—耳鼻咽喉科]