嘧霉胺在蓝莓中的残留行为及膳食风险评估  

Residue and dietary exposure risk assessment of pyrimethanil in blueberries

作　　者：马琳[1] 朱卫芳 占绣萍[1] 陈建波[1] 赵莉[1] MA Lin;ZHU Weifang;ZHAN Xiuping;CHEN Jianbo;ZHAO Li(Shanghai Agricultural Technology Extension and Service Center,Shanghai 201103,China;Shanghai Qingpu District Agricultural Product Quality and Safety Center,Shanghai 201700,China)

机构地区：[1]上海市农业技术推广服务中心,上海201103 [2]上海市青浦区农产品质量安全中心,上海201700

出　　处：《农药学学报》2022年第4期884-889,共6页Chinese Journal of Pesticide Science

基　　金：上海市科技兴农项目(2020-02-08-00-08-F01456).

摘　　要：为明确嘧霉胺在蓝莓上施用后可能产生的膳食暴露风险,通过规范的田间残留试验,检测了蓝莓中嘧霉胺的残留量,结合GEMS/FOOD中关于中国各年龄段居民97.5%位点的浆果类农产品膳食消费量及体重调查数据、每日允许摄入量(ADI),评估了嘧霉胺对中国各消费人群的长期膳食摄入风险。结果表明:在0.01~1 mg/kg添加水平范围内,嘧霉胺的平均回收率在97%~100%之间,相对标准偏差(RSD)在4.5%~12%之间;嘧霉胺在蓝莓中的检测方法定量限(LOQ)为0.01 mg/kg。露地栽培模式下,嘧霉胺在蓝莓中的消解速率符合一级反应动力学方程,消解半衰期为3.2 d。嘧霉胺按有效成分360 g/hm^(2)施药2次,每次间隔7 d,药后3、5、7、10 d时蓝莓中嘧霉胺的残留量为0.18~1.54 mg/kg。膳食风险评估表明,在膳食消费量97.5%位点处,蓝莓中嘧霉胺残留对各消费人群长期膳食摄入风险的贡献率小于0.1%,说明通过蓝莓摄入嘧霉胺残留对人体产生的长期膳食摄入风险较小。In order to assess the dietary exposure risk of pyrimethanil residue in blueberries,the terminal residues and decline trends of pyrimethanil used in blueberries were studied.The dietary exposure and risk assessment were conducted based on the supervised field trial data.The blueberries were sprayed in 2 times at an interval of 7 d with pyrimethanil at a dosage of 360 a.i.g/hm^(2).The results showed that the average recoveries of pyrimethanil in blueberry samples at five spiked levels from 0.01 mg/kg to 1 mg/kg were 97%-100%,with the relative standard deviation(RSD)ranged from 4.5%to 12%.The limits of quantification(LOQs)of pyrimethanil in blueberries was 0.01 mg/kg.The decline dynamics of pyrimethanil accorded with the first-order kinetics,and the half-lives of pyrimethanil was 3.2 d.At 3,5,7,10 days after the last application,the terminal residue levels of pyrimethanil at harvesting was 0.18-1.54 mg/kg.Chronic risk quotient of pyrimethanil was calculated from residue trial data,their acceptable daily intake,dietary consumption of berries in 97.5%and body weight of Chinese residents of all ages which from GEMS.The long-term dietary intake risk assessment at 97.5%food consumption showed that the contribution rate of blueberries residues to the ADI for all ages was less than 0.1%.This indicated that the chronic dietary intake risk of pyrimethanil through blueberries was very low.

关 键 词：嘧霉胺 蓝莓 农药残留 膳食暴露 风险评估 

分 类 号：TQ450.2[化学工程—农药化工] S482.2[农业科学—农药学]