异维A酸软胶囊联合玉屏风胶囊对外用重组人α-2b干扰素乳膏治疗面部扁平疣疗效的影响  

Effect of isotretinoin soft capsule combined with Yupingfeng capsule on the treatment of facia verruca plane with recombinant human interferon α-2b cream

作　　者：洪声 姚凤鸣 吴建华 HONG Sheng;YAO Feng-ming;WU Jian-hua(Department of Dermatology,Changhai Hospital,Naval Medical University,Shanghai 200433;Department of Dermatology,Anqing Hospital,Anhui Medical University,Anqing Anhui 246003,China)

机构地区：[1]海军军医大学第一附属医院皮肤科,上海200433 [2]安徽医科大学附属安庆医院皮肤科,安徽安庆246003

出　　处：《蚌埠医学院学报》2022年第7期887-888,892,共3页Journal of Bengbu Medical College

基　　金：全军后勤科研重大项目(AWS16J023)。

摘　　要：目的:研究外用重组人α-2b干扰素乳膏同时应用异维A软酸胶囊联合玉屏风胶囊对面部扁平疣的疗效。方法:对照组给予局部外用重组人α-2b干扰素乳膏,每天3次;观察组在对照组基础上给予口服异维A酸软胶囊和屏风胶囊;所有病人治疗疗程均为8周,观察治疗情况。结果:治疗后2组扁平疣皮损计数变化评分均明显低于治疗前,且观察组降低更明显,差异有统计学意义(P<0.01),观察组疗效明显优于对照组(P<0.01),观察组总有效率高于对照组(P<0.05)。2组均未出现明显不良反应。结论:异维A酸软胶囊联合玉屏风胶囊+外用重组人α-2b干扰素乳膏,三药合用治疗面部扁平疣是一种理想、高效的治疗方案。Objective:To explore the effects of the recombinant human interferon α-2 b cream, isotretinoin capsules combined with Yupingfeng capsule in the treatment of facial verruca plana.Methods:The control group was treated with recombinant human interferon α-2 b cream three times a day, and the observation group was additionally treated with isotretinoin capsules and Yupingfeng capsules on the basis of the control group.In two groups, the treatment course was 8 weeks, and the curative effects were observed.Results:After treatment, the scores of verruca plana count change in two groups were lower than that before treatment, the decreasing degree in the observation group was more obvious, and the difference of which was statistically significant(P<0.01).The curative effect in observation group was better than that in control group(P<0.01).The total effective rate in observation group was higher than that in control group(P<0.05).There were not obvious adverse reactions in two groups.Conclusions:The isotretinoin soft capsule combined with Yupingfeng capsule and external recombinant human interferon α-2 b cream is an ideal and efficient treatment for facial verruca plana.

关 键 词：扁平疣 异维A酸胶囊 玉屏风胶囊 重组人α-2b干扰素乳膏 

分 类 号：R752.52[医药卫生—皮肤病学与性病学]