盆腔器官脱垂患者焦虑、抑郁及生活质量测定量表最小临床重要性差值计算的临床意义  

The calculation of the minimal clinically important differences of anxiety,depression and quality of life scale in patients with pelvic organ prolapse

作　　者：熊正花 胡勇 张娟[1] 李晨[1] 李志红 卢绍波 龙熙翠 韩雪松[1] XIONG Zhenghua;HU Yong;ZHANG Juan;LI Chen;LI Zhihong;LU Shaobo;LONG Xicui;HAN Xuesong(Department of Gynecology,The first Affiliated Hospital of Kunming Medical University,Kunming 650032,China)

机构地区：[1]昆明医科大学第一附属医院妇科,650032

出　　处：《中国妇产科临床杂志》2022年第4期378-381,共4页Chinese Journal of Clinical Obstetrics and Gynecology

基　　金：国家自然科学基金项目(81960269)。

摘　　要：目的探讨手术治疗前后中重度盆腔器官脱垂(POP)患者的汉密顿焦虑量表(HAMA)、汉密顿抑郁量表(HAMD)和盆底功能障碍问卷简表-20(PFDI-20)及其分量表的最小临床重要性差值(MCID)。方法对113例中重度POP患者手术治疗前后HAMA、HAMD及PFDI-20量表进行评估,采用分布法计算HAMA、HAMD、PFDI-20及其分量表的MCID,并根据SPSS模拟结果选择量表的MCID并进行分析。结果中重度POP患者手术治疗前后焦虑测定量表HAMA的MCID为3.91,抑郁测定量表HAMD的MCID为2.25,生活质量测定量表PFDI-20及分量表POPDI-6、CRADI-8、UDI-6的MCID分别为81.70、24.79、8.69和34.50。结论POP患者手术治疗前后的HAMA、HAMD、PFDI-20及分量表评分变化值超过其MCID,差异具有临床意义。Objective To calculate the minimal clinical important differences(MCID)of Hamilton anxiety scale,Hamilton depression scale,Pelvic floor distress inventory-short form 20 and it’s subscale in patients with moderate to severe pelvic organ prolapse(POP)after surgery.Methods Selecting 113 patients with moderate to severe pelvic organ prolapse and evaluating the HAMA,HAMD and PFDI-20 before and after surgical treatment.So as to calculate the MCID of the scale by distribution method.Results The MCID of HAMA is 3.91.The MCID of HAMD is 2.25.The MCID of PFDI-20 and its subscales which are pelvic organ prolapse distress,Colorectal-anal distress and urinary distress are 81.70,24.79,8.69,34.50.Conclusion Changes in HAMA,HAMD,PFDI-20 and subscale scores of POP patients before and after surgical treatment exceeded their MCID.

关 键 词：盆腔器官脱垂 最小临床重要性差值 汉密顿焦虑量表 汉密顿抑郁量表 盆底功能障碍问卷 

分 类 号：R711.2[医药卫生—妇产科学]