人类细胞图谱的研究进展及展望  

Progress and prospects of The Human Cell Atlas

作　　者：陈雨巍 石毓君[1] CHEN Yuwei;SHI Yujun(Institute of Clinical Pathology,Key Laboratory of Transplant Engineering and Immunology,NHC,West China Hospital,Sichuan University,Chengdu 610041,P.R.China)

机构地区：[1]四川大学华西医院临床病理研究所卫健委移植工程与移植免疫重点实验室,成都610041

出　　处：《中国普外基础与临床杂志》2022年第7期850-851,共2页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：人类细胞图谱计划是继人类基因组计划后的又一项国际合作项目,致力于建立一个表征一切人体细胞的参考图谱。目前,这项计划已汇集了多份不同类型的图谱,但多专注于深入研究单个组织和器官的细胞类型。2022年5月12日,Science杂志发表了泛组织人类细胞图谱的最新研究成果,整合了人体多个组织和器官的细胞图谱,有助于更全面地了解疾病致病机制、疫苗研发、细胞工程、肿瘤免疫和再生药物开发。The Human Cell Atlas project is an international collaboration following the Human Genome Project,which aims to establish a reference map for the characterization of all human cells.Recent years,the project has brought together various different types of cell atlas,mostly focusing on the cell types of individual tissues and organs.Science published the latest research results of the Pan-tissue Human Cell Atlas on 12 May 2022,which integrates cell atlas of multiple tissues and organs in the human.It contributes to a more comprehensive understanding of disease pathogenesis,vaccine development,cell engineering,tumor immunity,and regenerative drug development.

关 键 词：人类细胞图谱 单细胞测序 人类生物学 免疫细胞 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学]