临床合理用药指导对2型糖尿病患者用药依从性的影响  

Influence of Clinical Rational Drug Use Guidance on Medication Compliance in Patients with Type 2 Diabetes Mellitus

作　　者：张涛 裴可灵 ZHANG Tao;PEI Keling(Shandong Electric Power Central Hospital,Ji'nan 250000,China;Shandong Province Mental Health Center,Ji'nan 250000,China)

机构地区：[1]山东电力中心医院,山东济南250000 [2]山东省精神卫生中心,山东济南250000

出　　处：《中国医药指南》2022年第20期10-13,共4页Guide of China Medicine

摘　　要：目的探讨临床合理用药指导对2型糖尿病患者用药依从性的影响。方法将84例2型糖尿病患者按密闭信封法分为两组,其中接受常规用药宣教的42例患者作为对照组,观察组42例患者在对照组基础上采用临床合理用药指导,比较两组患者的用药依从性、用药现状,评价患者血糖控制效果。结果观察组用药依从性(71.43%)高于对照组(33.33%),差异有统计学意义(P<0.05);观察组剂量不合理、服用时间不当、联合用药不合理总发生率(7.14%)低于对照组(28.57%),差异有统计学意义(P<0.05)。观察组护理后血糖指标水平均低于对照组,合理用药效能量表(SEAMS)评分高于对照组,差异有统计学意义(P<0.05)。观察组干预后FBG、2hPG及HbAc控制率分别为95.24%、97.62%、95.24%,均高于对照组的76.19%、76.19%、71.43%,差异有统计学意义(P<0.05)。观察组患者随访6个月期间低血糖事件发生率为2.38%,对照组低血糖事件发生率为19.05%,差异有统计学意义(P<0.05)。结论临床合理用药指导可提高2型糖尿病患者的用药依从性,有助于提高血糖控制效果。Objective To investigate the effect of clinical rational drug use guidance on medication compliance in patients with type 2 diabetes mellitus.Methods A total of 84 patients with type 2 diabetes were divided into two groups according to the closed envelope method.Among them,42 patients(control group)received conventional medication education.On the basis of the control group,42 patients(observation group)received clinical rational medication guidance.The medication compliance and medication status of the two groups of patients were compared,and the effect of blood sugar control was evaluated.Results The medication compliance of the observation group was better(71.43%)than that of the control group(33.33%),the difference was statistically significant(P<0.05).The total incidence of unreasonable dosage,improper taking time and unreasonable combination medication was 7.14%,lower than 28.57%of the control group,the difference was statistically significant(P<0.05).The levels of blood glucose indexes in the observation group after nursing were lower than those in the control group,and the score of the SEAMS was higher than that in the control group,the difference was statistically significant(P<0.05).After intervention,the control rates of FBG,2hPG and HbAc in the observation group were 95.24%,97.62%,95.24%,respectively,which were higher than 76.19%,76.19%,71.43%in the control group,the differences were statistically significant(P<0.05).During the 6-month follow-up period,the incidence of hypoglycemia in the observation group was 2.38%,and the incidence of hypoglycemia in the control group was 19.05%,the difference was statistically significant(P<0.05).Conclusion The clinical rational drug use guidance can improve the medication compliance of patients with type 2 diabetes mellitus and help improve the effect of blood sugar control.

关 键 词：临床合理用药指导 2型糖尿病 用药依从性 血糖 

分 类 号：R587.1[医药卫生—内分泌] R969.3[医药卫生—内科学]