益生菌对肠道微生态系统及肥胖调节作用研究进展  

Research progress of probiotics on intestinal microecosystem and obesity regulation

作　　者：李秀凉 尹欣[1,2] LI Xiu-liang;YIN Xin(Engineering Research Center of Agricultural Microbiology Technology,Ministry of Education,Heilongjiang University,Harbin 150500,China;Key Laboratory of Molecular Biology,College of Heilongjiang Province,School of Life Sciences,Heilongjiang University,Harbin 150080,China)

机构地区：[1]黑龙江大学农业微生物技术教育部工程研究中心,黑龙江哈尔滨150500 [2]黑龙江大学生命科学学院,黑龙江省普通高校分子生物学重点实验室,黑龙江哈尔滨150080

出　　处：《生物技术》2022年第3期380-386,共7页Biotechnology

基　　金：黑龙江省自然科学基金面上项目(C2006049);哈尔滨市应用研究与开发项目(青年后备人才A类RC2017QN020010)。

摘　　要：目前,肥胖发病率显著增加。肥胖会导致高血脂、高血压、2型糖尿病等疾病的发生,威胁着人类的健康。研究表明,肥胖人群与瘦弱人群肠道微生态系统组成不同,而利用益生菌调节肠道微生态系统是预防和治疗肥胖的方法之一。该文综述了肠道微生态系统对肥胖的影响,益生菌对肠道微生态系统的调节作用,益生菌基于肠道微生态系统对肥胖的调节途径的最新研究进展,为益生菌在调节肠道微生态系统及预防和治疗肥胖方面研究提供参考。The incidence rate of obesity has increased significantly.Obesity can lead to diseases such as hyperlipidemia,hypertension,Type 2 diabetes and so on.Studies have shown that the composition of intestinal micro-ecosystem is different between obese people and thin people,and the regulation of intestinal micro-ecosystem by probiotics is one of the methods to prevent and treat obesity.This paper reviews the impact of intestinal micro-ecosystem on obesity,the regulatory effect of probiotics on intestinal micro-ecosystem,and the latest research progress of probiotics based on intestinal micro-ecosystem on obesity,so as to provide reference for the research of probiotics in regulating intestinal micro ecosystem and preventing and treating obesity.

关 键 词：肥胖 肠道微生态系统 益生菌 调节途径 

分 类 号：R589.2[医药卫生—内分泌]