心脏淀粉样变性临床研究进展  

Clinical Research of Cardiac Amyloidosis

作　　者：杜明亮 郑晓群[1] DU Mingliang;ZHENG Xiaoqun(Cardiology Department,Dalian Central Hospital,Dalian 116032,Liaoning,China)

机构地区：[1]大连市中心医院心血管内科,辽宁大连116032

出　　处：《心血管病学进展》2022年第7期636-639,644,共5页Advances in Cardiovascular Diseases

摘　　要：心脏淀粉样变性通常表现为限制性的心力衰竭和多浆膜腔积液。心电图表现为肢体低电压、胸导联R波递增不良;在超声心动图上表现为双心房增大,左心室室壁厚度增加,左心室腔不大,左心室舒张功能减退,或有颗粒状心肌强回声等改变;心脏磁共振表现为特征性的心肌延迟强化;组织活检在偏振光显微镜下具有典型的苹果绿双折射和刚果红染色。现通过对心脏淀粉样变性的临床症状及相关实验室结果的讨论,旨在加强临床医师对该疾病的认识。Cardiac amyloidosis is often manifested as restricted heart failure,multiple serous cavity effusion.Electrocardiogram showed limb low voltage and poor increase of R wave in chest lead.On echocardiography,it showed enlargement of both atria and increased left ventricular wall thickness,small left ventricular cavity,decreased left ventricular diastolic function,changes of granular myocardial strong echo.Cardiac magnetic resonance imaging showed characteristic late gadolinium enhancement.The biopsies showed typical apple green birefringence and Congo red staining under polarized light microscope.In this paper,the clinical symptoms and laboratory results of cardiac amyloidosis are discussed to enhance the understanding of clinicians about this disease.

关 键 词：心脏淀粉样变性 限制型心肌病 诊断 

分 类 号：R541[医药卫生—心血管疾病]