盐酸坦索罗辛治疗输尿管远段小结石的效果研究  

Study on the effect of tamsulosin hydrochloride in the treatment of small distal ureteral calculi

作　　者：李志雄[1] 米其武[1] 罗杰鑫[1] 叶照华[1] 黄荏钊[1] 卢健军 LI Zhi-xiong;MI Qi-wu;LUO Jie-xin(Department of Urology,Dongguan People's Hospital,Dongguan 523000,China)

机构地区：[1]东莞市人民医院泌尿外科,523000

出　　处：《中国实用医药》2022年第15期135-137,共3页China Practical Medicine

摘　　要：目的 探讨盐酸坦索罗辛治疗输尿管远段小结石的效果。方法 124例输尿管远段小结石患者,以随机数字表法分为对照组和治疗组,各62例。对照组予以解痉药物、非甾体类阵痛抗炎药及尿石通丸治疗,治疗组则在对照组基础上加用盐酸坦索罗辛治疗。比较两组临床效果、并发症发生情况。结果 治疗组结石排出时间(5.82±3.17)d短于对照组的(9.38±3.26)d,强力止痛剂使用率22.58%低于对照组的45.16%,结石排出率88.71%高于对照组的54.84%,差异有统计学意义(P<0.05)。治疗组并发症发生率为4.84%低于对照组的17.74%,差异有统计学意义(P<0.05)。结论 在输尿管远段小结石治疗中应用非甾体类抗炎药物、解痉药物、排石颗粒的基础上增加盐酸坦索罗辛,治疗效果显著,且临床常见症状的发生较少,治疗成功率高,值得推广和应用。Objective To discuss the effect of tamsulosin hydrochloride in the treatment of small distal ureteral calculi.Methods A total of 124 patients with small distal ureteral calculi were randomly divided into the control group and the treatment group,with 62 cases in each group.The control group was treated with antispasmodic drugs,non-steroidal analgesic anti-inflammatory drugs and Niaoshitong pills,and the treatment group was additionally treated with tamsulosin hydrochloride on the basis of the control group.The clinical effects and complications were compared between the two groups.Results The stone expulsion time(5.82±3.17)d in the treatment group was shorter than(9.38±3.26)d in the control group,the use rate of strong analgesics 22.58%was lower than 45.16%in the control group,and the stone expulsion rate 88.71%was higher than 54.84%in the control group.All the differences were statistically significant(P<0.05).The complication rate in the treatment group was 4.84%,which was lower than 17.74%in the control group,and the difference was statistically significant(P<0.05).Conclusion The addition of tamsulosin hydrochloride on the basis of antispasmodic drugs,non-steroidal analgesic anti-inflammatory drugs and Niaoshitong pills is significantly effective in the treatment of small distal ureteral calculi,with less occurrence of common clinical symptoms and high success rate of treatment,which is worthy of promotion and application.

关 键 词：输尿管远段小结石 盐酸坦索罗辛 非甾体类阵痛抗炎药 尿石通丸 

分 类 号：R693.4[医药卫生—泌尿科学]