眩晕汤联合甲磺酸倍他司汀片治疗良性阵发性位置性眩晕手法复位后残留眩晕的临床效果  

Clinical effects of Xuanyun Decoction combined with Betahistine Mesylate Tablets for treatment of residual dizziness after manual reduction of benign paroxysmal positional vertigo

作　　者：林爱桃 古联[2] 陈敏丽 宋潇宵 梁一帆 黄先利 唐略均 杨俊威 LIN Ai-tao;GU Lian;CHEN Min-li;SONG Xiao-xiao;LIANG Yi-fan;HUANG Xian-li;TANG Lue-jun;YANG Jun-wei(Graduate School,Guangxi University of Chinese Medicine,Nanning 530001,China;The Second Department of Encephalopathy,the First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530023,China)

机构地区：[1]广西中医药大学研究生学院,南宁市530001 [2]广西中医药大学第一附属医院脑病科二区,南宁市530023

出　　处：《广西医学》2022年第11期1212-1214,1224,共4页Guangxi Medical Journal

基　　金：广西中医药大学研究生教育创新计划(YCXJ2021053);广西中医药大学校级科研项目(2019MS025);广西中医药大学第一附属医院院级课题(2021QN008)。

摘　　要：目的观察眩晕汤联合甲磺酸倍他司汀片治疗良性阵发性位置性眩晕(BPPV)手法复位后残留眩晕的临床效果。方法选择90例BPPV手法复位后残留眩晕的患者,将其随机分成3组,每组30例。A组给予甲磺酸倍他司汀片治疗,B组给予眩晕汤治疗,C组给予眩晕汤联合甲磺酸倍他司汀片治疗。3组患者均连续治疗14 d。观察3组患者治疗3 d、7 d后的临床疗效,治疗前1 d、治疗7 d和14 d后的眩晕障碍量表(DHI)评分,以及治疗后1个月、3个月、6个月的复发情况。结果治疗3 d后,B组和C组的临床疗效均优于A组;治疗7 d后,C组的临床疗效优于A组和B组,而B组优于A组(均P<0.05)。治疗7 d、14 d后,DHI得分均A组>B组>C组(均P<0.05)。治疗后1个月、3个月及6个月,C组的复发率均低于A组和B组(均P<0.05)。结论眩晕汤联合甲磺酸倍他司汀片治疗BPPV手法复位后残留眩晕的临床效果显著,与单一药物治疗相比,其可更好地改善患者的头晕症状,降低复发率,值得临床推广。Objective To observe the clinical effects of Xuanyun Decoction combined with Betahistine Mesylate Tablets for treating residual dizziness after manual reduction of benign paroxysmal positional vertigo(BPPV).Methods Ninety BPPV patients with residual dizziness after manual reduction were selected and randomly assigned to three groups,with 30 patients in each group.Group A was administrated Betahistine Mesylate Tablets,group B was treated with Xuanyun Decoction,whereas group C was administrated Xuanyun Decoction combined with Betahistine Mesylate Tablets.A continuous 14-day treatment was given to patients of the three groups.The clinical efficacy three and seven days after treatment,the Dizziness Handicap Inventory(DHI)scores one day before treatment,and seven,14 days after treatment,and the recurrence conditions one,three and six months after treatment were observed in patients of the three groups.Results Groups B and C exhibited a superior clinical efficacy to group A three days after treatment.After seven days of treatment,group C achieved a superior clinical efficacy to groups A and B,and group B was superior to group A(all P<0.05).The score of DHI seven and 14 days after treatment presented in a descending sequence as follows:group A,group B,group C(all P<0.05).Group C yielded lower recurrence rates in comparison with groups A and B one,three,and six months after treatment(all P<0.05).Conclusion Xuanyun Decoction combined with Betahistine Mesylate Tablets exerts a significant clinical effect in the treatment of residual dizziness after manual reduction of BPPV,which can preferably ameliorate the dizziness symptom and decrease the recurrence rate in the patients as compared with the monotherapy,deserving to promote in clinics.

关 键 词：良性阵发性位置性眩晕 手法复位 残留眩晕 甲磺酸倍他司汀 眩晕汤 

分 类 号：R764[医药卫生—耳鼻咽喉科]