导管/静脉直径比预测血液肿瘤患者有症状性PICC相关血栓的研究  

Catheter to vein ratio predicts symptomatic venous thromboembolism related to peripherally inserted central catheter in patients with hematologic malignancy

作　　者：许汇娟[1] 刘颖[1] 姚嘉丽[1] 姚晶晶[1] 陈敏[1] 邱甜甜 Xu Huijuan;Liu Ying;Yao Jiali;Yao Jingjing;Chen Min;Qiu Tiantian(Department of Hematology,Nanfang Hospital of Nanfang University,Guangzhou 510515,China)

机构地区：[1]南方医科大学南方医院血液科,广东广州510515

出　　处：《护理学杂志》2022年第13期44-48,共5页Journal of Nursing Science

基　　金：南方医科大学南方医院院长基金立项资助项目(2020H009)。

摘　　要：目的探讨PICC导管/静脉直径比在预测血液肿瘤患者有症状性导管相关血栓的最佳临界值。方法选取留置PICC的273例血液肿瘤患者作为研究对象,根据患者临床症状结合彩超监测有症状性血栓发生情况,通过logistic回归分析和受试者工作特征曲线确定导管/静脉直径比最佳临界值。结果6.23%患者发生了有症状性导管相关血栓。导管/静脉直径比35%~45%、≥46%的患者发生导管相关血栓的的风险分别是≤34%患者的16.762、15.529倍。导管/静脉直径比38%是预测导管相关血栓的最佳临界值。结论导管/静脉直径比与血液肿瘤患者PICC导管有症状性血栓的发生密切相关,临床置管操作时,应尽可能保证该比值≤38%。Objective To explore the optimal cut-off value of catheter to vein ratio(CVR)in predicting symptomatic venous thromboembolism(VTE)related to peripherally inserted central catheter(PICC)in patients with hematologic malignancy.Methods A total of 273 patients with hematologic malignancy who had a PICC were studied.Symptomatic VTE was diagnosed based on patient′s clinical symptoms and Ultrasonic color Doppler.The optimal cut-off value of CVR was determined by logistic regression analysis and receiver operating characteristic(ROC)curve.Results The prevalence of symptomatic VTE was 6.23%.Compared with CVR less than or equal to 34%,CVR between 35%and 45%,≥46%had odds ratios of 16.762 and 15.529 respectively.ROC analysis determined that a 38%CVR was the ideal cut off point.Conclusion There is a close relationship between CVR and risk of PICC symptomatic VTE,and CVR less than or equal to 38%is recommended.

关 键 词：血液肿瘤 PICC 导管/静脉比 有症状性血栓 最佳临界值 

分 类 号：R473.73[医药卫生—护理学]