3121例出生缺陷儿情况回顾性分析  

Retrospective analysis on 3121 birth defect monitoring infants

作　　者：陈少稚 章建伟[1] 李可心 CHEN Shao-Zhi;ZHANG Jian-Wei;LI Ke-Xin(Shaoxing Maternity and Child Health Care Hospital,Shaoxing,Zhejiang 312000,China)

机构地区：[1]绍兴市妇幼保健院保健部,浙江绍兴312000

出　　处：《中国妇幼保健》2022年第12期2284-2287,共4页Maternal and Child Health Care of China

基　　金：浙江省医药卫生科技计划项目(2021KY1155)。

摘　　要：目的了解绍兴市近3年出生缺陷情况及其动态变化趋势,为降低出生缺陷干预措施的制定提供理论依据。方法数据来源于2018年1月—2020年12月绍兴地区医院监测的3121例出生缺陷儿资料,对该数据进行整理分析。结果近3年绍兴地区男性围生儿出生缺陷率显著高于女性(χ^(2)=6.384,P=0.041);城市围生儿出生缺陷率高于农村(χ^(2)=35.846,P<0.001);产妇年龄<20岁组与>35岁组分别在2018-2019年、2020年围生儿出生缺陷率占比高;低龄产妇与高龄产妇比较,差异有统计学意义(χ^(2)=43.224,P<0.001)。2018-2020年围生儿先天性心脏病发生率最高。结论先天性心脏病居于围生儿出生缺陷儿的首位,男性、城市、孕产妇年龄<20岁和≥35岁是围生儿出生缺陷的主要影响因素。加大重点疾病及因素的监测与防控,对预防新生儿缺陷、促进母婴保健具有重要意义。Objective This study aimed to investigate the situation and dynamic change of birth defects in Shaoxing area in recent 3 years,so as to provide theoretical basis for formulating intervention measures to reduce birth defects.Methods We mainly collected and analyzed the information of 3121 cases of birth defects on newborn in Shaoxing region from January 2018-December 2020.Results In recent three years,the rate of birth defect in boys was significantly higher than that in girls in this area(χ^(2)=6.384,P=0.041).The rate of birth defect in urban areas was higher than that in rural areas(χ^(2)=35.846,P<0.000).The perinatal birth defect rates were significantly increased in the group of maternal age<20 and>35 years,respectively,from 2018 to 2019 and 2020;there were significant differences between younger and older women(χ^(2)=43.224,P<0.000),and the highest incidence of defects was still congenital heart defects.Conclusion Congenital heart disease was the most common cause of birth defects.Male,urban and maternal age<20 and≥35 years were the main influencing factors of perinatal birth defects.Therefore,it is veryimportant to strengthen the monitoring and prevention,control of key diseases to prevent newborn defects and promote maternal and infant health care.

关 键 词：围生儿死亡 医院监测 出生缺陷 先天性心脏病 

分 类 号：R714[医药卫生—妇产科学]