机构地区:[1]辽宁中医药大学附属医院,辽宁沈阳110032
出 处:《辽宁中医药大学学报》2022年第6期65-69,共5页Journal of Liaoning University of Traditional Chinese Medicine
基 金:国家重点研发计划(2018YFC1705203);国家中医药管理局第六批全国老中医药专家学术经验传承项目。
摘 要:目的探究自拟温阳通痹汤联合隔姜灸治疗寒湿痹阻型尪痹的临床疗效。方法纳入2019年1月—2020年12月间于该院诊治的寒湿痹阻型尪痹患者,共123例。根据123例患者的就诊时间随机分为常规治疗组(常规组)、常规治疗联合中药汤剂组(中药组)、常规治疗加中药汤剂联合隔姜灸组(联合组),每组各41例。常规组入院后接受基础治疗,根据不同病情,按照主治医师拟定的治疗方案进行,并按照尪痹的中医护理原则进行起居、生活等方面指导。中药组在常规组治疗的基础上,口服自拟温阳通痹汤,早晚饭后各150 mL温服。患者每服完一疗程中药后,均需进行中医辨证论治,进行临证调方。联合组在中药组治疗的基础上实施隔姜灸,每日1次,均在下午施灸。本研究共进行15 d,中间(第8天)休息1 d。对所有患者治疗前后及组间的中医主症及次症积分、SF-MPQ量表评分、血清中类风湿因子(RF)、C反应蛋白(CRP)、血沉(ESR)水平及治疗有效率进行统计对比。结果治疗前三组的中医主症积分和次症积分、SF-MPQ总分和各维度得分、RF、CRP、ESR水平差异无统计学意义(P>0.05),具有可比性。治疗结束后三组的中医主症积分和次症积分、SF-MPQ总分和各维度得分、RF、CRP、ESR水平均较治疗前有所改善(P<0.05),各组组间比较显示上述指标的改善程度由高到低为联合组>中药组>常规组,且差异均具有统计学意义(P<0.05)。治疗后三组的治疗有效率为常规组82.93%,中药组85.37%,联合组97.56%,联合组有效率最高,且差异均具有统计学意义(P<0.05)。结论自拟温阳通痹汤联合隔姜灸可通过降低CRP、ESR、RF水平,从而达到改善寒湿痹阻型尪痹患者关节损伤和疼痛水平及中医临床症状的治疗效果。Objective To explore the clinical curative effect of self-made Wenyang Tongbi Decoction(温阳通痹汤)combined with ginger-separated moxibustion in the treatment of Wangbi with cold-dampness obstruction syndrome.Methods A total of 123 patients with cold-dampness obstruction syndrome of Wangbi diagnosed and treated in our hospital from January 2019 to December 2020 were included.According to the visit time of 123 patients,they were randomly divided into conventional treatment group(conventional group),conventional treatment combined with traditional Chinese medicine decoction group(Chinese medicine group),conventional treatment plus traditional Chinese medicine decoction combined with ginger moxibustion group(combined group),41 persons in each group.The study was approved by the ethics committee of our hospital and accepted its supervision throughout the process.The conventional group received basic treatment after admission,according to different conditions,according to the treatment plan drawn up by the attending physician,and guided daily life and life in accordance with the principles of traditional Chinese medicine nursing.In the traditional Chinese medicine group,on the basis of the conventional treatment,the self-made Wenyang Tongbi Decoction was taken orally,150 mL each in the morning and evening after meals.After taking a course of traditional Chinese medicine,patients need to undergo dialectical treatment and clinical prescriptions.The combined group implemented ginger-separated moxibustion on the basis of the treatment of the Chinese medicine group,once a day,both in the afternoon.The study was conducted for 15 days,with one day off in the middle(the eighth day).The scores of major and minor symptoms of traditional Chinese medicine before and after treatment and between groups,SFMPQ scale scores,serum rheumatoid factor(RF),C-reactive protein(CRP),erythrocyte sedimentation rate(ESR)levels,and treatment effective rate of all patients were compared.Results Before treatment,there was no significant differ
分 类 号:R255.6[医药卫生—中医内科学]
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