红芪临床应用研究新进展  

New Progress in Clinical Application of Hongqi(Hedysari Radix)

作　　者：冯慧敏 李成义[1] 李玥 罗旭东[1] 梁婷婷 贾妙婷 强正泽[1] 魏小成 周瑞娟[1] 张广袤 FENG Huimin;LI Chengyi;LI Yue;LUO Xudong;LIANG Tingting;JIA Miaoting;QIANG Zhengze;WEI Xiaocheng;ZHOU Ruijuan;ZHANG Guangmao(Gansu University of Chinese Medicine,Lanzhou 730000,Gansu,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730000

出　　处：《中华中医药学刊》2022年第6期61-65,共5页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金(81860683);甘肃省教育厅双一流重大科研项目(甘财教〔2021〕35);甘肃省教育厅2018高校科研项目成果转化项目(2018D-17);甘肃省中药质量与标准研究重点实验室开放基金(zyzx-2020-26)。

摘　　要：红芪为甘肃的大宗药材,主要含有红芪多糖、黄酮、苯丙素、三萜及甾体类化合物、微量元素、生物碱、有机酸等化学成分。在临床上应用广泛,其药理研究主要集中在糖尿病及其并发症、肿瘤、衰老、肺纤维化、肝损伤、骨质疏松、炎症(肠炎、葡萄膜炎、骨关节炎)、阿尔茨海默病等病证的防治。通过文献检索,梳理和总结了近几年国内外红芪药理作用及临床应用研究,体现其在临床应用优势和开发前景。Hongqi(Hedysari Radix)as a bulk medicinal material in Gansu Province,mainly contains Hedysarum Polybotys saccharide,flavonoids,phenylpropanoid,triterpenoids and steroids,trace elements,alkaloids,organic acids and other chemical components.It is widely used in clinical practice,and its pharmacological research mainly focuses on the prevention and treat-ment of diabetes and its complications,tumors,senescence,pulmonary fibrosis,liver injury,osteoporosis,inflammation(enteritis,u-veitis,osteoarthritis),Alzheimer's disease and other diseases.In this paper,the pharmacological effects and clinical application of Hedysari Radix at home and abroad in recent years were reviewed and summarized to reflect its advantages and development pros-pects in clinical application.

关 键 词：红芪 糖尿病及其并发症 红芪多糖 药理作用 

分 类 号：R282.71[医药卫生—中药学]