银杏叶胶囊联合尼可地尔对冠状动脉粥样硬化心脏病心绞痛的临床效果研究  

Clinical Effect of Ginkgo Biloba Capsule Combined with Nicorandil on Coronary Atherosclerotic Heart Disease and Angina Pectoris

作　　者：李兴文 Li Xing-wen(Yanggu County Hospital of Traditional Chinese Medicine,Liaocheng 252300,Shandong Province,China)

机构地区：[1]阳谷县中医医院,山东聊城252300

出　　处：《中国社区医师》2022年第20期57-59,共3页Chinese Community Doctors

摘　　要：目的:研究分析银杏叶胶囊联合尼可地尔用药对冠状动脉粥样硬化心脏病心绞痛的临床治疗效果。方法:选取2020年2月-2021年2月阳谷县中医医院收治的120例冠状动脉粥样硬化心脏病心绞痛患者,均分为研究组和对照组,各60例。研究组采用银杏叶胶囊联合尼可地尔治疗,对照组单纯给予尼可地尔用药治疗。比较两组患者临床疗效、心绞痛发作情况、炎性因子和不良反应发生率。结果:研究组总有效率高于对照组,差异有统计学意义(P<0.05)。治疗前两组患者心绞痛发作情况比较,差异无统计学意义(P>0.05);治疗后两组心绞痛发作次数、硝酸甘油用量、心绞痛发作持续时间均有所降低,其中研究组降低水平优于对照组,差异有统计学意义(P<0.05)。治疗前两组患者的炎性因子比较,差异无统计学意义(P>0.05);治疗后两组炎性因子水平均有所降低,其中研究组降低水平优于对照组,差异有统计学意义(P<0.05)。研究组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论:对冠状动脉粥样硬化心脏病心绞痛患者采用银杏叶胶囊联合尼可地尔治疗的临床效果更加显著,且用药后能有效改善患者心绞痛症状,消除炎症,治疗安全性高。coronary atherosclerotic heart disease and angina pectoris.Methods:A total of 120 patients with coronary atherosclerotic heart disease and angina pectoris admitted to Yanggu County Hospital of Traditional Chinese Medicine from February 2020 to February2021 were selected and equally divided into a study group and a control group,with 60 cases in each group.The study group was treated with ginkgo biloba capsules combined with nicorandil,and the control group was treated with nicorandil alone.The clinical efficacy,angina pectoris attack,inflammatory factors and incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in angina pectoris attacks between the two groups(P>0.05);after treatment,the number of angina pectoris attacks,the dosage of nitroglycerin,and the duration of angina pectoris attacks in the two groups were decreased,and the decreased level in the study group was better than that in the control group,the difference was statistically significant(P<0.05).There was no significant difference in the inflammatory factors between the two groups before treatment(P>0.05);after treatment,the levels of inflammatory factors in the two groups were decreased,and the decreased level in the study group was better than that in the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:The clinical effect of binkgo biloba capsule combined with nicorandil in the treatment of coronary atherosclerotic heart disease patients with angina pectoris is more significant,and the treatment can effectively improve the symptoms of angina pectoris,eliminate inflammation,and has high treatment safety.

关 键 词：银杏叶胶囊 尼可地尔 冠状动脉粥样硬化 心脏病 心绞痛 

分 类 号：R541.4[医药卫生—心血管疾病]