禁欲天数之差对连续两次精液常规检查精子质量的影响  

Effect of the difference of abstinence days on sperm quality after two consecutive routine semen analysis

作　　者：张国忠 胡艳梅[1] 张玲 张曦予 ZHANG Guozhong;HU Yanmei;ZHANG Ling;ZHANG Xiyu(Reproductive Medicine Center,Panzhihua City Maternal and Child Health Hospital,Panzhihua,Sichuan 617000,China)

机构地区：[1]攀枝花市妇幼保健院生殖医学中心,四川攀枝花617000

出　　处：《国际检验医学杂志》2022年第15期1839-1842,1848,共5页International Journal of Laboratory Medicine

基　　金：四川省医学青年创新科研课题计划(Q20011);四川省攀枝花市指导性科技计划项目(2020ZD-S-18)。

摘　　要：目的探讨不育男性患者连续两次精液常规检查时,禁欲天数之差(第2次精液常规检查禁欲天数减去第1次精液常规检查禁欲天数的绝对值)对精子质量的影响。方法回顾性分析2018年8月至2021年3月就诊于该院的466例男性不育患者连续两次精液常规检查结果及相关资料,根据禁欲天数之差将患者分为0 d组(138例)、1 d组(164例)、2 d组(84例)、3 d组(51例)、4 d组(18例)和≥5 d组(11例)。比较6组患者两次精液常规检查的精液参数(精液量、pH值、精子浓度、精子总数、精子前向运动百分率和精子总活力),分析不同禁欲天数之差及两次精液常规检查与精液参数的相关性。结果6组间两次精液常规检查中精子前向运动百分率、精子总活力差异均有统计学意义(P<0.05),其中0 d组两次精液常规检查中精子前向运动百分率、精子总活力与其他5组比较,差异均有统计学意义(P<0.05);同组两次精液常规检查结果比较,精子前向运动百分率、精子总活力差异均有统计学意义(P<0.05)。精液常规检查次数、禁欲天数之差与精子前向运动精子百分率、精子总活力均呈正相关(r>0,P<0.05)。结论连续两次精液常规检查禁欲天数之差增加,可改善精子前向运动百分率和精子总活力,但为了减少精液常规检查结果的差异,建议多次精液常规检查前禁欲天数尽量相同,以便为临床诊断提供更加准确的检查结果。Objective To investigate the effect of the difference of abstinence days(absolute value of abstinence days of the second semen routine examination minus abstinence days of the first semen routine examination)on sperm quality in infertile male patients with two consecutive semen routine examinations.Methods The results and related data of two consecutive routine semen examination of 466 male infertile patients who visited this hospital from August 2018 to March 2021 were analyzed retrospectively.The patients were divided into 0 d group(138 cases),1 d group(164 cases),2 d group(84 cases),3 d group(51 cases),4 d group(18 cases)and≥5 d group(11 cases)according to the difference of abstinence days.The semen parameters(semen volume,pH value,sperm concentration,total sperm count,percentage of sperm forward movement and total sperm motility)of two routine semen examinations in 6 groups were compared,and the correlation among the difference of different abstinence days and two semen routine tests and semen parameters were analyzed.Results There were statistically significant differences in the percentage of sperm forward movement and total sperm motility of the two routine semen examinations among the six groups(P<0.05),and there were statistically significant differences in the percentage of sperm forward movement and total sperm motility of the two routine semen examinations between the 0 d group and the other 5 groups(P<0.05).Compared with the results of the two routine semen examinations in the same group,there were statistically significant differences in the percentage of sperm forward movement and total sperm motility(P<0.05).The frequency of routine semen examination and the difference of abstinence days were positively correlated with the percentage of sperm forward movement and total sperm motility(r>0,P<0.05).Conclusion The increase of the difference of abstinence days between two consecutive semen routine examinations can improve the percentage of sperm forward movement and total sperm motility,but in order

关 键 词：不育 精液常规检查 禁欲天数之差 精液参数 

分 类 号：R698.2[医药卫生—泌尿科学]