体检男性良性前列腺增大伴前列腺钙化的相关因素  

Related Factors of Benign Prostatic Enlargement with Prostate Calcification in Men Receiving Physical Examinations

作　　者：张小马[1,2] 肖莉 林长明 张力 周骏[1] 郝宗耀[1] 梁朝朝[1] ZHANG Xiao-ma;XIAO Li;LIN Chang-ming;ZHANG Li;ZHOU Jun;HAO Zong-yao;LIANG Chao-zhao(Department of Urology,The First Affiliated Hospital of AnHui Medical University,Hefei 230022,China;Depart-ment of Urology,The Fourth Affiliated Hospital of AnHui Medical University,Hefei 230012,China;Department of Health Management Center,The Fourth Affiliated Hospital of AnHui Medical University,Hefei 230012,China)

机构地区：[1]安徽医科大学第一附属医院泌尿外科,安徽合肥230022 [2]安徽医科大学第四附属医院泌尿外科,安徽合肥230012 [3]安徽医科大学第四附属医院健康管理中心,安徽合肥230012

出　　处：《中山大学学报（医学科学版）》2022年第4期600-606,共7页Journal of Sun Yat-Sen University:Medical Sciences

基　　金：国家自然科学基金(81870519)。

摘　　要：【目的】前列腺钙化(PC)影响良性前列腺增大(BPE)导致的下尿路症状(LUTS),为了BPE者PC的防治提供参考,本研究探讨体检男性BPE伴PC的相关因素。【方法】回顾性分析2018年10月至2021年6月3433名在安徽医科大学第四附属医院体检男性中863例BPE的临床资料,单因素分析比较A组(BPE伴PC)和B组(BPE不伴PC)血、尿等指标参数,Logistic回归分析BPE伴PC的相关因素。【结果】BPE(定义为前列腺体积≥20 mL)伴PC在BPE者中的发生率为37.5%(324/863)。A组年龄、血尿素氮、尿PH值高于B组(P<0.05),身高、体质量、血尿酸低于B组(P<0.05),前列腺回声不均者比例高于B组(P<0.05),两组间代谢综合征及组分者比例无差异(P>0.05)。Logis⁃tic回归分析显示前列腺回声不均、尿PH值和年龄(尤其80~89岁)是体检BPE者BPE伴PC的相关因素[OR 95%CI为2.082(1.111,3.900);OR 95%CI为1.419(1.152,1.747)和OR 95%CI为17.829(3.224,98.594)]。【结论】体检BPE者BPE伴PC的发生率较高。除年龄外,前列腺回声不均和尿PH值也是体检BPE者BPE伴PC的相关因素。【Objective】Lower urinary tract symptoms(LUTS)caused by benign prostatic enlargement(BPE)are influenced by prostate calcification(PC).The aim of this study is to explore the related factors of BPE with PC in men re⁃ceiving physical examinations,and to provide some references for the prevention and treatment of PC in BPE patients.【Methods】The clinical data of 863 cases of BPE among 3433 men who underwent physical examination in the Fourth Affil⁃iated Hospital of Anhui Medical University from October 2018 to June 2021 were analyzed retrospectively The blood and urine examination indexes between group A(BPE with PC)and group B(BPE without PC)were compared by univariate analysis.The related factors of BPE with PC were analyzed by logistic regression【.Results】The incidence of BPE(defined as prostate volume≥20 mL)with PC in BPE patients was 37.5%(324/863).Univariate analysis showed that age,blood urea nitrogen,and urinary pH value in group A were significantly higher than those in group B(P<0.05),and height,weight and blood uric acid of group A were lower than those of group B group(P<0.05).The proportion of patients with in⁃homogeneous prostatic echo in group A was higher than that in group B(P<0.05).There was no significant difference in the proportion of patients with metabolic syndrome and components between the two groups(P>0.05).Multivariate logistic regression analysis showed that inhomogeneous echo of the prostate,urinary pH and age(especially 80~89 years old)were the related factors of BPE with PC in BPE patients undergoing checkups[OR 95%CI 2.082(1.111,3.900);OR 95%CI 1.419(1.152,1.747)and OR 95%CI 17.829(3.224,98.594)]【.Conclusions】The incidence of BPE with PC in BPE pa⁃tients undergoing checkups is higher.In addition to age,inhomogeneous echo of the prostate and urine pH are related fac⁃tors for BPE with PC in BPE patients undergoing physical examinations.

关 键 词：良性前列腺增大 前列腺钙化 健康体检 相关因素 

分 类 号：R697.32[医药卫生—泌尿科学]