3%HS与0.9%NS雾化溶液在中重度毛细支气管炎患儿雾化治疗中的应用效果对比及对睡眠质量的影响  

Comparison of the effect of 3%HS and 0.9%NS atomizing solution in atomizing treatment of children with moderate and severe bronchiolitis and its influence on sleep quality

作　　者：呼争艳 王娜[1] 周晓娜[1] 贾瑞杰 Hu Zheng-yan;Wang Na;Zhou Xiao-na(Children's Hospital affiliated to Zhengzhou University,Henan Children's Hospital,Zhengzhou Children's Hospital,Zhengzhou 450000,China;Neonatal Internal Care Unit,Children's Hospital of Zhengzhou University,Henan Children's Hospital,Zhengzhou Children's Hospital,Zhengzhou 450000,China)

机构地区：[1]郑州大学附属儿童医院,河南省儿童医院,郑州儿童医院消毒供应中心,河南郑州450000 [2]郑州大学附属儿童医院,河南省儿童医院,郑州儿童医院新生儿内科监护室,河南郑州450000

出　　处：《四川生理科学杂志》2022年第7期1153-1155,共3页Sichuan Journal of Physiological Sciences

摘　　要：目的:探究应用3%高渗盐水(Hypertonic saline,HS)与0.9%生理盐水(Physiological saline,NS)雾化溶液对中重度毛细支气管炎患儿进行治疗后,对患儿治疗效果及睡眠质量的影响。方法:选取郑州大学附属儿童医院、河南省儿童医院、郑州儿童医院新生儿内科监护室2018年9月至2020年12月期间93例中重度毛细支气管炎患儿为研究对象,随机分为两组,均给予综合常规治疗,其中46例对照组患儿将雾化吸入药物溶于0.9%NS溶液进行雾化吸入,47例观察组患儿给予3%HS雾化吸入,对比两组患儿的相关诊疗指标。结果:观察组患儿干预有效率明显高于对照组(P<0.05);观察组患儿咳嗽、肺部哮鸣音、肺部啰音、喘息缓解时间,住院时间,临床严重度评分等各项指标均低于对照组(P<0.05);实施干预后,观察组患儿夜间睡眠时间高于对照组、夜醒次数低于对照组(P<0.05)。结论:3%HS雾化溶液可以提高中重度毛细支气管炎患儿的预后效果,改善各项临床效果指标,提高患儿睡眠质量。Objective:To investigate the effects of 3%Hypertonic saline(HS)and 0.9%Physiological saline(NS)atomizing solution on the treatment effect and sleep quality of children with moderate and severe bronchiolitis.Methods:A total of 93 children with moderate to severe bronchiolitis were selected from the Children's Hospital affiliated to Zhengzhou University,Henan Children's Hospital,and the Neonatal Internal Care Unit of Zhengzhou Children's Hospital from September 2018 to December 2020.They were randomly divided into two groups and received comprehensive routine treatment.Among them,46 children in the control group were given atomized inhalation with atomized drugs dissolved in 0.9%NS solution,and 47 children in the observation group were given 3%HS atomized inhalation.The related diagnosis and treatment indicators of the two groups were compared.Results:The effective rate of intervention in observation group was significantly higher than that in control group(P<0.05).Cough,pulmonary wheezing,pulmonary rales,respite time,hospital stay,Clinical severity score(CSS)and other indicators in the observation group were lower than those in the control group(P<0.05).After intervention,in the observation group,the sleep time was longer,and wake times were less than those in the control group(P<0.05).Conclusion:3%HS atomized solution can improve the prognosis of children with moderate and severe bronchiolitis,improve various clinical effect indicators,and improve the sleep quality of children.

关 键 词：雾化溶液 中重度毛细支气管炎 患儿 雾化治疗 睡眠质量 

分 类 号：R72[医药卫生—儿科]