硬化性肺细胞瘤的MSCT特征及^(18)F-FDGPET/CT表现  

Pulmonary sclerosing pneumocytoma of the lung:MSCT and ^(18)F-FDG PET/CT imaging characteristics

作　　者：张曦 秦显莉 符海杰 张静娜[3] 张晔[3] 韩一飞 Zhang Xi;Qin Xianli;Fu haijie;Zhang Jingna;Zhang Ye;Han Yifei(Department of Radiology,XinQiao Hospital,the Third Military Medical University,Chongqing 400037,China;Department of Nuclear Medicine,XinQiao Hospital,the Third Military Medical University,Chongqing 400037,China;Department of Medical Informatics and Medical Image,College of Biomedical Engineering and Image,Chongqing 300038,China)

机构地区：[1]陆军(第三)军医大学第二附属医院放射科,重庆400037 [2]陆军(第三)军医大学第二附属医院放射科核医学科,重庆400037 [3]陆军(第三)军医大学生物医学工程与影像学院医学信息与医学图像学教研室,重庆400038

出　　处：《中华肺部疾病杂志（电子版）》2022年第3期300-305,共6页Chinese Journal of Lung Diseases(Electronic Edition)

基　　金：国家自然科学基金青年基金项目(81802253)。

摘　　要：目的分析肺硬化性肺细胞瘤(pulmonary sclerosing pneumocytoma,PSP)的临床特征、多层螺旋CT(multislice spiral computed tomography,MSCT)和^(18)F-FDGPET/CT特征,提高PSP术前诊断水平及认识。方法选择2013年9月至2021年11月我院经手术病理证实后55例PSP患者,分析临床及影像学特征,包括48例CT平扫、33例CT增强、19例18 F-FDGPET/CT全身显像,进一步分析病灶分布、形态、大小、伴随征象、代谢摄取结果,进一步分析了病灶最大直径与最大标准化摄取值(SUV max)相关性。结果MSCT显示病灶多为单发(94.5%),边界光滑(89%),呈圆形或椭圆形(85.5%),平均直径25.6 mm。CT主要征象包括贴边血管征(45.5%)、晕征(12.7%)、空气新月征(16.4%)和钙化(41.8%)。增强扫描延迟期趋向均匀持续强化。19例PSP病灶SUV_(max),平均值为(2.87±1.20),病灶SUV_(max)与最大长径呈显著正相关(R=0.51,P<0.001)。结论“血管贴边征”、“空气新月征”、“晕征”、“钙化”等特征性PSP患者具有特征性MSCT表现,PSP病灶^(18)F-FDG PET/CT以中低代谢摄取为主,其大小可能与摄取FDG增加有关,MSCT影像征象、^(18)F-FDG PET/CT代谢摄取为正确诊断PSP提供了理论依据。Objective To describe the detailed clinical,to analyze the detailed clinical features,Imaging Characteristics of PSP under multislice spiral computed tomography(MSCT),and ^(18)F-fluorodeoxy glucose positron emission tomography(^(18)F-FDG PET/CT),in order to improve the preoperative diagnosis.Methods A total of 55 patients with PSP confirmed by surgical pathology were included,48 cases received CT plain scan,33 cases received CT enhanced scan and 19 cases received 18 F-FDGPET/CT imaging.The distribution,morphology,size,clinicoradiological signs and metabolic uptake results of lesions were further analyzed.the relationship between maximum standardized uptake value(SUV_(max))and maximum diameter of lesions were observed.Results Most patients had a single lesion(94.5%),smooth boundary(89%),and round or oval shape(85.5%),and the mean diameter was 25.6 mm.The mainCT signs included vessel marginal sign(45.5%),halo sign(12.7%),air crescent sign(16.4%)and calcification(41.8%).Delayed phase of Enhanced scanning tends to be continuous and homogeneous enhanced.Besides,The mean maximum standardized uptake value on FDG PET of 19 patients was(2.87±1.20).the maximum standardized uptake value(SUV_(max))of 19 patients were significantly positively correlated with the maximum diameter of lesions(R=0.51,P<0.001).Conclusion Imaging Characteristics of PSP in MSCT is special,such as vessel marginal sign,halo sign,air crescent sign and calcification.And the 18 F-FDGPET/CT scan revealed hypometabolic FDG uptake in the patients with PSP,which may be related to the increased uptake of FDG.MSCT imaging signs and ^(18)F-FDGPET/CT metabolic uptake provide a theoretical basis for the correct diagnosis of PSP.

关 键 词：肺硬化性肺泡细胞瘤 体层摄影术 正电子发射断层成像 多层螺旋CT 氟代脱氧葡萄糖 

分 类 号：R563[医药卫生—呼吸系统]