单采血小板献血者输血相关传染病标志物筛查结果分析  

Analysis of the screening results of transfusion-associated infectious disease markers in apheresis platelets blood donors

作　　者：涂东晋[1] 林海娟[1] TU Dongjin;LIN Haijuan(Fujian Province Blood Center,Fuzhou,Fujian 350004,China)

机构地区：[1]福建省血液中心,福建福州350004

出　　处：《检验医学与临床》2022年第15期2101-2104,共4页Laboratory Medicine and Clinic

摘　　要：目的分析福州地区2014—2020年单采血小板献血者输血相关传染病标志物筛查不合格情况的变化,探讨降低筛查不合格率的措施,减少单采血小板的报废。方法回顾性分析2014—2020年福州地区60735例单采血小板献血者的血液筛查结果,对不合格指标进行分析。结果福州地区单采血小板献血者输血相关传染病标志物筛查不合格率为0.73%,各年度筛查总不合格率比较差异有统计学意义(P<0.05),丙氨酸氨基转移酶(ALT)和核酸扩增检测技术(NAT)是主要不合格项;不同性别和不同年龄段筛查总不合格率比较差异均有统计学意义(P<0.05),全血献血者的筛查总不合格率高于单采血小板献血者(P<0.05)。结论应规范献血前的健康咨询和体检初筛工作,加强试剂和设备管理,做好献血者的屏蔽与归队工作,减少血液的报废,防止不必要的血源流失。Objective To investigate the changes of unqualified situation about transfusion-associated infectious disease markers in Fuzhou area from 2014 to 2020,and to discuss the measures on reducing the unqualified rate,and reducing the scrap of apheresis platelet samples.Methods The blood screening results of 60735 apheresis platelet donors in Fuzhou area from 2014 to 2020 were retrospectively analyzed,and the unqualified indicators were analyzed.Results The unqualified rate of the transfusion-associated infectious disease markers in Fuzhou area was 0.73%,the differences of the unqualified rate among different years were statistically significant(P<0.05).Alanine aminotransferase(ALT)and nucleic acid amplification technology(NAT)were the main unqualified items,the differences of the unqualified rate between different genders and different age groups were statistically significant(P<0.05).The unqualified rate of the whole blood donors was higer than that of apheresis platelets blood donors(P<0.05).Conclusion The health consultation and preliminary screening of physical examination before blood donation should be standardized,the management of reagents and equipment should be strengthened,a good job in screening and returning blood donors should be conducted,in order to reduce the scrapping of blood,and prevent unnecessary blood loss.

关 键 词：单采血小板 献血者 输血相关传染病标志物 筛查 

分 类 号：R446.1[医药卫生—诊断学]