一例大林羚肠毒血症的诊断  

Diagnosis of a Case of Enterotoxaemia in a Common Eland(Tragelaphus oryx)

作　　者：郑秉武 智宇 李彦军 丁玉林[4] 高雅[4] 刘佳利 张承天 王金玲[4] ZHENG Bingwu;ZHI Yu;LI Yanjun;DING Yulin;GAO Ya;LIU Jiali;ZHANG Chengtian;WANG Jinling(Hohhot Zoo,Hohhot,010050,China;Inner Mongolia Academy of Agricultural&Animal Husbandry Sciences,Hohhot,010051,China;Inner Mongolia Alashan Youqi Center for Animal Disease Control and Prevention,Alashan Youqi,737300,China;College of Veterinary Medicine,Inner Mongolia Agricultural University,and Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease,Ministry of Agriculture and Rural Affairs,Hohhot,010010,China)

机构地区：[1]呼和浩特市动物园,呼和浩特010050 [2]内蒙古自治区农牧业科学院,呼和浩特010051 [3]内蒙古阿拉善右旗动物疫病预防控制中心,阿拉善右旗737300 [4]内蒙古农业大学兽医学院和农业农村部动物疾病临床诊疗技术重点实验室,呼和浩特010010

出　　处：《野生动物学报》2022年第3期788-792,共5页CHINESE JOURNAL OF WILDLIFE

基　　金：内蒙古自治区科技重大专项课题(2021ZD0012)。

摘　　要：通过临床病史、剖检病变、组织病理学、触片检查和毒素试验方法确诊了1例大林羚(Tragelaphus oryx)肠毒血症。1只15岁大林羚无任何临床症状突然死亡,尸体角弓反张,典型病变为十二指肠和空肠严重出血性肠炎,肠壁变薄,肠管内有较多黑红色血样内容物,肠黏膜呈弥漫性暗红色与黑红色,皱胃黏膜有大小不等的出血性坏死灶。特征性组织学病变为严重的出血性坏死性肠炎、中毒性肝损伤和中毒性肾损伤。十二指肠和空肠黏膜层出血、坏死,多数区域呈均质红染;肝细胞和肾小管上皮细胞严重变性、散在坏死。在肠黏膜触片上可见散在或成簇分布的单个或成双的革兰阳性粗大的产气荚膜梭菌(Clostridium perfringens)。小白鼠毒素试验结果显示,接种肠内容物后13~18 h试验小白鼠均死亡。In this study,clinical symptom,autopsy,histopathology,impression smears and toxin experiment were used to diagnose a case of enterotoxaemia in an adult common eland(Tragelaphus oryx).A 15-year-old eland died suddenly in the early morning without showing any clinical symptoms.At autopsy,the dead body showed opisthotonos.The typical lesions were severe hemorrhagic enteritis of the small intestine,with thinning wall of the duodenum and jejunum,more blood content in the intestinal lumen,and diffuse dark red and black red intestinal mucosa.There are hemorrhagic necrotic foci of varying sizes on the mucosa of abomasum.Histopathologically,the characteristic lesions include severe hemorrhagic necrotizing enteritis,toxic liver injury and toxic kidney injury.The mucosa of duodenum and jejunum were hemorrhagic and necrotic,showing homogeneous red staining.Diffuse degeneration and sporadic necrosis of hepatocytes and renal tubular epithelial cells were observed.Numerous single or paired gram-positive Clostridium perfringens were seen on the impression smears of the intestinal mucosa.The results of toxin test in mice showed that all mice died 13-18 hours after the intestinal contents were inoculated.

关 键 词：大林羚 肠毒血症 出血性坏死性肠炎 中毒性肝损伤 产气荚膜梭菌 

分 类 号：S858.9[农业科学—临床兽医学]