高度近视合并屈光参差性弱视患者与非弱视患者空间扭曲特征对比分析  

Comparison of binocular spatial distortion in high-myopia anisometropic patients with and without amblyopia

作　　者：李晓霞 林彩霞 张熙芳 褚航 阎丽 乔利亚 LI Xiaoxia;LIN Caixia;ZHANG Xifang;CHU Hang;YAN Li;QIAO Liya(Department of Ophthalmology,Beijing Shijitan Hospital of Capital Medical University,Beijing 100038,China;Beijing Tongren Eye Center,Beijing Key Laboratory of Ophthalmology and Visual Science,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,Beijing,China;National Engineering Research Center for Healthcare Devices,Guangzhou 512511,Guangdong Province,China)

机构地区：[1]首都医科大学附属北京世纪坛医院眼科,北京市100038 [2]首都医科大学附属北京同仁医院北京同仁眼科中心眼科学与视觉科学北京市重点实验室,北京市100730 [3]国家医疗保健器具工程技术研究中心,广东省广州市512511

出　　处：《眼科新进展》2022年第8期630-633,共4页Recent Advances in Ophthalmology

基　　金：首都医科大学附属北京世纪坛医院青年基金(编号:2018-q21)。

摘　　要：目的探讨高度近视合并屈光参差性弱视患者与非弱视患者空间扭曲特征差异。方法选取2019年5月至2020年1月就诊于北京同仁医院的高度近视合并屈光参差患者50例作为研究对象。根据患者最佳矫正视力(BCVA)(≥0.8)分为非弱视组和弱视组,非弱视组患者21例,弱视组患者29例。采用国家医疗保健器具工程技术研究中心开发研制的视感知觉检查评估系统检测患者空间扭曲情况,检测时视标“○”沿着3个直径分别为3.6°、4.4°和5.2°的同心圆随机闪现,受试者将“+”套入“○”后点击鼠标,将结果记录为空间扭曲距离(SDD)和空间扭曲角度(SDA),两者计量单位分别为像素和度(°),箭头的头尾距离为SDD,与水平线夹角为SDA,在小、中、大三个同心圆分别记录为SDDs、SDDm、SDDl和SDAs、SDAm、SDAl。使用SPSS 22.0对数据进行统计学分析。结果弱视组患者双眼SDD较非弱视组明显增大,除SDDm外(P=0.20),SDDs和SDDl两组间差异均有统计学意义(均为P<0.05);弱视组患者双眼SDA较非弱视组明显增大,除SDAm外(P=0.25),SDAs和SDAl两组间差异均有统计学意义(均为P<0.05)。高度近视合并屈光参差性弱视患者视觉空间扭曲更明显。但是,也存在一些非弱视患者具有明显空间扭曲,而部分弱视患者无明显空间扭曲的现象。结论高度近视合并屈光参差性弱视患者较非弱视患者具有更明显空间扭曲,其可能参与弱视的发生发展。Objective To explore the binocular spatial distortion(SD)characteristics of high-myopia anisometropic patients with and without amblyopia.Methods A total of 50 patients with high myopia and anisometropia treated in Beijing Tongren Hospital from May 2019 to January 2020 were recruited in this study.According to the best corrected visual acuity(BCVA)(≥0.8),they were divided into the non-amblyopic(21 patients)and amblyopic groups(29 patients).The SD was detected by a visual perception examination and evaluation system invented by the National Engineering Research Center for Healthcare Devices.During the detection,the visual target“○”randomly flashed point by point around three concentric circles with different diameters(3.6°,4.4°,and 5.2°,respectively).Patients put“+”into“○”and clicked a mouse button.The distance from head to tail of the arrow was recorded as spatial distortion distance(SDD),and the angle of the arrow with the horizontal line was recorded as spatial distortion angle(SDA).SDD and SDA were expressed with pixels and°,respectively.SDD and SDA in small,middle,and large circles were measured as SDDs,SDDm,SDDl,and SDAs,SDAm,SDAl,respectively.SPSS 22.0 was used for statistical analysis.Results Amblyopic patients exhibited increased binocular SDD and SDA compared with non-amblyopic patients.Except SDDm(P=0.20),the two groups showed significant differences in SDDs and SDDl(both P<0.05).Except SDAm(P=0.25),the two groups showed significant differences in SDAs and SDAl(both P<0.05).The binocular SD was more obvious in amblyopic patients.However,some non-amblyopic patients showed significant SD,whereas some amblyopic patients showed no significant SD.Conclusion High-myopia anisometropic patients with amblyopia have much more binocular SD than patients without amblyopia.SD may be involved in the occurrence and development of amblyopia.

关 键 词：空间扭曲 高度近视 屈光参差 弱视 

分 类 号：R777.4[医药卫生—眼科]