急性肾损伤患者肾脏替代治疗何时停机  

When to stop renal replacement therapy in patients with acute kidney injury

作　　者：薛瑾虹 陈蕾[1] 魏萌[1] 严森辉 蒋红利[1] XUE Jinhong;CHEN Lei;WEI Meng;YAN Senhui;JIANG Hongli(Department of Blood Purification,the First Affiliated Hospital of Xi’an Jiaotong University,Xi’an,Shaanxi 710061,P.R.China)

机构地区：[1]西安交通大学医学院第一附属医院血液净化科,西安710061

出　　处：《华西医学》2022年第7期974-978,共5页West China Medical Journal

基　　金：陕西省重点研发计划-国际科技合作计划项目一般项目(2021KW-44);西安交通大学医学院第一附属医院院级基金(2020ZYTS-13)。

摘　　要：急性肾损伤是重症患者常见的并发症,其发病率和病死率均高,连续性肾脏替代治疗(continuous renal replacement therapy,CRRT)是该病最重要的治疗方法之一。CRRT的启动时机与停机时机是临床医生经常要抉择的问题,CRRT停机过早可能导致患者治疗不充分,病情反复,增加不良预后,但CRRT的过度治疗则可能会延长住院时间,增加医疗费用,增加CRRT相关并发症的风险。该文针对CRRT何时停机这一问题,综合国内外相关资料,就临床指标以及相关生物标志物的研究进展作一总结。Acute kidney injury is a common complication in the critically ill patients with high morbidity and mortality.Continuous renal replacement therapy(CRRT)is one of the most important treatments for the disease.The timing of starting and stopping of CRRT is often a matter of choice for clinicians.Early stopping of CRRT may lead to inadequate treatment,recurrent disease and poor prognosis,while excessive treatment of CRRT may prolong the hospital stay,increase medical costs and increase the risk of CRRT-related complications.In order to illustrate the proper stopping time of CRRT,this paper summarizes the research progress of the clinical indicators and biomarkers by reviewing relevant domestic and foreign data.

关 键 词：急性肾损伤 连续性肾脏替代治疗 停机时机 

分 类 号：R692[医药卫生—泌尿科学]