基于聚N-乙烯基吡咯烷酮的两亲性嵌段共聚物  

Preparation and Application of Amphiphilic Block Copolymers Based on Poly(N-vinylpyrrolidone)

作　　者：张禄练 杨龙花 宝利军 彭小琼 谢广帆 毕韵梅[1] Zhang Lulian;Yang Longhua;Bao Lijun;Peng Xiaoqiong;Xie Guangfan;Bi Yunmei(College of Chemistry,Yunnan Normal University,Kunming 650500,China)

机构地区：[1]云南师范大学化学化工学院,云南昆明650500

出　　处：《云南化工》2022年第8期7-9,共3页Yunnan Chemical Technology

基　　金：国家自然科学基金项目(No:21564017)。

摘　　要：聚N-乙烯基吡咯烷酮(PNVP)具有优异的水溶性、化学稳定性和良好的生物相容性,可作为亲水性嵌段构成两亲性嵌段共聚物,在药物控释释放、靶向释放、防污涂料等方面具有广阔的应用前景。归纳总结了含PNVP的两亲性嵌段共聚物的制备方法及其应用,并在此基础上对PNVP的两亲性嵌段共聚物的发展趋势和研究方向进行了展望。Poly(N-vinylpyrrolidone)(PNVP)has excellent water solubility,chemical stability and good biocompatibility.It can be used as a hydrophilic block to constitute an amphiphilic block copolymer.Amphiphilic block copolymers based on poly(N-vinylpyrrolidone)have broad application prospects in drug control and targeted release,antifouling coatings,etc.In this paper,the preparation methods and applications of PNVP-containing amphiphilic block copolymers are summarized,and on this basis,the development trend and research direction of PNVP-containing amphiphilic block copolymers are prospected.

关 键 词：聚N-乙烯基吡咯烷酮(PNVP) 两亲性嵌段共聚物 表面活性剂 

分 类 号：TQ423[化学工程]