急性肾损伤标志物应用价值:现状与未来  

Analysis of application value on acute kidney injury biomarkers

作　　者：孙涛 陶志华[1] Sun Tao;Tao Zhihua(Department of Laboratory Medicine,the Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China)

机构地区：[1]浙江大学医学院附属第二医院检验科,杭州310009

出　　处：《中华检验医学杂志》2022年第7期671-676,共6页Chinese Journal of Laboratory Medicine

摘　　要：急性肾损伤是临床常见的疾病,发病率与病死率逐年增加,给国家与社会经济带来沉重的负担。早期诊断与早期干预急性肾损伤能够显著降低疾病的发生与进展。因此,寻找早期敏感、特异、经济的生物标志物尤为重要。近年来,血液与尿液中的蛋白质作为急性肾损伤的标志物被逐渐挖掘与研究,涉及基础与临床研究的多个层面。Acute kidney injury is a common and severe clinical event,the morbidity and mortality of acute kidney injury are increasing steadily,which is related with heavy burden to the country and social economy.Early diagnosis and intervention could significantly reduce the occurrence and progression of acute kidney injury.Therefore,it is of particular importance to find sensitive,specific,and economic biomarkers for acute kidney injury.In recent years,efforts have been made on exploring proteins in blood and urine as biomarkers of acute kidney injury.Present review summarizes progress in this field based on results of recent basic and clinical research.

关 键 词：急性肾损伤 生物标志物 

分 类 号：R692[医药卫生—泌尿科学]