A novel phosphorylation site in SARS-CoV-2 nucleocapsid regulates its RNA-binding capacity and phase separation in host cells  

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作  者:Junyu Wu Yongheng Zhong Xue Liu Xiaoyu Lu Weijie Zeng Chunyan Wu Fan Xing Liu Cao Fuxiang Zheng Panpan Hou Hong Peng Chunmei Li Deyin Guo 

机构地区:[1]Centre for Infection and Immunity Study(CIIS),School of Medicine,Shenzhen Campus of Sun Yat-sen University,Shenzhen 518197,China

出  处:《Journal of Molecular Cell Biology》2022年第2期72-75,共4页分子细胞生物学报(英文版)

基  金:supported by the National Natural Science Foundation of China(32041002 to D.G.and 31800151 to J.W.);Guangdong Province‘Pearl River Talent Plan’Innovation and Entrepreneurship Team Project(2019ZT08Y464 to C.L.);Shenzhen Science and Technology Program(JSGG20200225150431472 and KQTD20180411143323605 to D.G.,GXWD20201231165807008 and 20200825183117001 to J.W.).

摘  要:Dear Editor,The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is a novel emerging coronavirus that has spread worldwide since breaking out in late 2019 and has led to hundreds of millions of infections and millions of human deaths(Zhou et al.,2020).The genome of SARS-CoV-2 encodes 29 viral proteins.

关 键 词:ACUTE RESPIRATORY 

分 类 号:R373[医药卫生—病原生物学] R563.1[医药卫生—基础医学]

 

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