补肾健脾调周法结合董氏奇穴针法治疗多囊卵巢综合征临床研究  

Treatment principle of invigorating the spleen and kidney and regulating menstrual cycle combined with Dong's extra-point acupuncture for the patients with polycystic ovary syndrome

作　　者：凌桂梅[1] 农惠玲[1] 朱博杰 Ling Guimei;Nong Huiling;Zhu Bojie(Department of TCM,People's Hospital of Baise,Baise 533000,China)

机构地区：[1]百色市人民医院中医科,百色533000

出　　处：《国际中医中药杂志》2022年第7期759-763,共5页International Journal of Traditional Chinese Medicine

摘　　要：目的评价补肾健脾调周法结合董氏奇穴针法治疗PCOS的临床疗效。方法将符合入选标准的2020年1-12月本院PCOS患者70例,采用随机数字表法分为西药组23例、调周组23例与联合组24例,西药组口服以炔雌醇环丙孕酮片,调周组予以补肾健脾调周法治疗,联合组予以补肾健脾调周法+董氏奇穴针法治疗。3组均持续治疗3个月经周期。分别于治疗前后采用全自动免疫发光分析仪检测睾酮、雌二醇、FSH、LH水平,以彩色多普勒超声诊断仪检测卵巢,记录卵巢体积和直径<10 mm的卵泡数量,记录不良反应,评价临床疗效。结果西药组总有效率为52.17%(12/23)、调周组为60.87%(14/23)、联合组为87.50%(21/24),3组比较差异有统计学意义(P<0.05)。联合组治疗后睾酮[(1.02±0.12)μg/L比(1.23±0.25)μg/L、(1.46±0.19)μg/L,F=30.47]、雌二醇[(40.18±12.31)ng/L比(48.62±12.58)ng/L、(50.73±12.37)ng/L,F=4.78]、LH[(6.87±2.45)U/L比(8.28±2.29)U/L、(8.54±2.51)U/L,F=3.26]水平低于调周组与西药组(P<0.05)。联合组治疗后卵巢体积[(7.05±2.34)m3比(8.79±2.11)m3、(9.12±2.18)m3,F=5.97]小于调周组和西药组(P<0.05),直径<10 mm卵泡数量[(8.28±2.24)个比(9.67±2.40)个、(10.15±2.64)个,F=3.77]少于调周组和西药组(P<0.05)。治疗期间,西药组不良反应发生率为21.7%(5/23)、调周组为13.0%(3/23)、联合组为8.3%(2/24),3组比较差异无统计学意义(P>0.05)。结论补肾健脾调周法结合董氏奇穴针法可有效调节PCOS患者的性激素水平,促进卵泡发育和排卵,改善卵巢形态,且安全性较好。Objective To evaluate the clinical curative effect of invigorating the spleen and kidney and regulating menstrual cycle treament combined with Dong's extra-point acupuncture on polycystic ovary syndrome(PCOS).Methods According to random number table method,70 patients with PCOS meeting inclusion criteria in the hospital were divided into western medicine group(23 cases),TCM group(23 cases)and combination group(24 cases)between January and December 2020.The western medicine was treated with ethinylestradiol and cyproterone acetate tablets,TCM group was treated with invigorating the spleen and kidney and regulating menstrual cycle treatment,and combination group was treated with invigorating the spleen and kidney and regulating menstrual cycle treatment and Dong's extra-point acupuncture.All the three groups were treated continuously for 3 menstrual cycles.Before and after treatment,levels of testosterone,estradiol,FSH and LH were detected by full-automatic immunoluminescence analyzer.The ovaries were detected by color Doppler ultrasound diagnostic apparatus.The ovarian volume,number of follicles and adverse reactions were recorded.The clinical curative effect was evaluated.Results The differences in total response rate among western medicine group,TCM group and combination group were statistically significant[52.17%(12/23),60.87%(14/23)vs.87.50%(21/24),P<0.05].After treatment,levels of testosterone[(1.02±0.12)μg/L vs.(1.23±0.25)μg/L,(1.46±0.19)μg/L,F=30.47],estradiol[(40.18±12.31)ng/L vs.(48.62±12.58)ng/L,(50.73±12.37)ng/L,F=4.78]and LH[(6.87±2.45)U/L vs.(8.28±2.29)U/L,(8.54±2.51)U/L,F=3.26]in combination group were significantly lower than those in the TCM group and western medicine group(P<0.05).After treatment,ovarian volume[(7.05±2.34)m3 vs.(8.79±2.11)m3,(9.12±2.18)m3,F=5.97]in combination group was significantly lower than that in TCM group and western medicine group(P<0.05),and number of follicles(<10 mm)(8.28±2.24 vs.9.67±2.40,10.15±2.64,F=3.77)was significantly lower than that of TCM grou

关 键 词：多囊卵巢综合征 补肾健脾调周法 董氏奇穴针法 治疗 临床研究性 

分 类 号：R271.9[医药卫生—中西医结合]