环状RNA与糖尿病及其并发症的研究进展  

Research advances in the study of circRNA and diabetes mellitus and its complications

作　　者：巴涛 常向云[1] 朱余蓉[1] BA Tao;CHANG Xiangyun;ZHU Yurong(Department of Endocrinology and Metabolism,The First Hospital of Shihezi University School of Medicine,Shihezi 832000,China)

机构地区：[1]新疆石河子大学医学院第一附属医院内分泌代谢科,832000

出　　处：《中国糖尿病杂志》2022年第7期551-553,共3页Chinese Journal of Diabetes

基　　金：国家自然科学基金(81860149);石河子大学校级科研项目(ZZZC2020T3A)。

摘　　要：DM是一种由遗传、环境等多因素共同作用的代谢紊乱性疾病,随着病程进展出现各种并发症。近年来,人们对非编码RNA的研究取得重大突破,环状RNA(circRNA)是一种新型非编码RNA,呈首尾相接的闭合环状结构。circRNA广泛参与细胞代谢调控网络,在DM及其并发症中发挥重要作用,有望成为新的分子标志物。本文对circRNA与DM及其并发症的研究进展进行综述。Diabetes mellitus(DM)is a metabolic disorder caused by heredity and environment.With the progress of the disease,various complications may appear. In recent years,great breakthroughs have been made in the research of noncoding RNA. Circular RNA(circRNA)is a new noncoding RNA with a closed ring structure connected head to tail. CircRNA is widely involved in cellular metabolic regulatory network,which may play an important role in DM and its complications,and is expected to become a new molecular marker. This paper reviews the research progress of the relationship between circRNA and DM and its complications.

关 键 词：circRNA 糖尿病 并发症 

分 类 号：R587.2[医药卫生—内分泌]