Acupuncture for dystonia in brain-type Wilson’s disease with internal retention of damp heat pattern:A randomized clinical trail  

针刺治疗湿热内蕴型肝豆状核变性脑型肌张力障碍——随机临床试验

作　　者：Ping WANG Huai-zhen CHEN Luo-yi LI Jun YANG Wen-ming YANG Pin WANG 王萍;陈怀珍;李落意;杨骏;杨文明;王频(安徽中医药大学第一附属医院,中国合肥230031;安徽中医药大学,中国合肥230031)

机构地区：[1]The First Affiliated Hospital of Anhui University of Chinese medicine,Hefei 230031,China [2]Anhui University of Chinese Medicine,Hefei 230031,China

出　　处：《World Journal of Acupuncture-Moxibustion》2022年第3期193-198,共6页世界针灸杂志（英文版）

摘　　要：Objective:To observe the clinical efficacy of acupuncture on dystonia in brain-type Wilson’s disease(WD)with internal retention of damp heat pattern.Methods:A total of 60 patients with WD dystonia with internal retention of damp heat pattern were randomized into acupuncture and medication groups using a random number table,with 30 participants in each group.All patients had a low-copper diet and consumed dimercaptopropanesulfonate sodium(DMPS) for copper excretion.In the acupuncture group,on the base of the same treatment as that given to the medication group,acupuncture was applied at Baihui(百会GV20),Shenting(神庭GV24),Chéngjiāng(承浆CV4),Jiānyú(肩髃L15),Nàoshū(臑俞SI10),Wàiguān(外关TE5),Nèiguān(内关PC6),Shǒusānlǐ(手三里LI10),Hégǔ(合谷LI4),Yángxī(阳溪LI5),Huántiào(环跳GB30),Bìguān(髀关ST31),Yánglíngquán(阳陵泉GB34),Fēnglóng(丰隆ST40),Zúsānlǐ(足三里ST36),Sānyīnjiāo(三阴交SP6),Xuánzhōng(悬钟GB39),and Xíngjiān(行间LR2).Before and 24 days after treatment,the modified Ashworth scale(MAS) and BurkeFahn-Marsden dystonia rating scale(BFMDRS) were used to evaluate dystonia symptoms.The allocation scheme was concealed for the outcome assessors.Results:The data of 30 cases were analyzed in each group.Before treatment,the MAS score difference between the acupuncture and medication groups was not statistically significant(P> 0.05).Compared with the score before treatment,the MAS score was lower significantly in both the acupuncture group(2.63±0.76 vs 4.50 ± 0.78) and medication group(3.30 ± 0.65 vs 4.40 ± 0.77) after treatment(both P <0.05).After treatment,the MAS score in the acupuncture group was significantly lower than that in the medication group(P <0.01).Before treatment,the BFMDRS score was not significantly different between the two groups(P> 0.05).Compared with the score before treatment,the BFMDRS score was significantly lower in both the acupuncture(64.97 ± 14.26 vs 85.23± 16.99) and medication groups(11.33 ± 2.60 vs 75.40 ± 16.

关 键 词：ACUPUNCTURE Wilson’s disease Brain-type DYSTONIA Dimercaptopropansulfonate sodium 

分 类 号：R246.6[医药卫生—针灸推拿学]