北京市男男性行为者对HIV暴露前预防知晓和需求及影响因素分析  

Awareness and demand of men who have sex with men for HIV pre-exposure prophylaxis and its influencing factors in Beijing

作　　者：陈鹏[1] 王丽娟[2] 张丽芬[2] 李东亮[2] CHEN Peng;WANG Li-juan;ZHANG Li-fen;LI Dong-liang(Baotou Medical College,Inner Mongolia University of Science and Technology,Neimenggu 014040,China)

机构地区：[1]内蒙古科技大学包头医学院,014040 [2]北京市朝阳区疾病预防控制中心

出　　处：《首都公共卫生》2022年第3期152-156,共5页Capital Journal of Public Health

基　　金：国家科技重大专项(编号:2018ZX10715-005)。

摘　　要：目的了解北京市男男性行为者(men who have sex with men,MSM)对HIV暴露前预防(pre-exposure prophylaxis,PrEP)的知晓、使用意愿和客观需求情况,为推广PrEP提供参考依据。方法2020年12月-2021年5月,通过社会小组招募最近一年内有过同性性行为的男性作为研究对象。利用“问卷星”电子调查平台收集人口学信息、艾滋病相关知识和行为、对PrEP服务的认知、使用意愿及客观需求情况。分析调查对象HIV暴露前预防知晓、使用意愿、客观需求情况及其影响因素。结果共调查297人,其中有效问卷288份,有效应答率96.97%。61.11%(176/288)知晓PrEP,37.15%(107/288)有PrEP客观需求,知晓PrEP者中88.64%(156/176)有PrEP使用意愿,9.66%(17/176)答对全部PrEP相关问题。多因素回归分析显示:半年内同性性伴数≥6(aOR=6.553,95%CI:1.777~24.162),最近一年使用过暴露后预防(aOR=9.034,95%CI:2.072~39.393),最近一年患过性病者(aOR=4.606,95%CI:1.005~21.108)PrEP知晓率更高;文化程度为大专及以上者(aOR=4.669,95%CI:1.718~12.687),存在PrEP客观需要者(aOR=5.056,95%CI:1.384~18.474)PrEP使用意愿更强烈。结论北京市MSM对PrEP知晓率较高,但对具体内容掌握程度较低,对PrEP有较高水平客观需求和使用意愿,故应继续强化PrEP推广工作,并适时广泛开展PrEP服务,让真正需要PrEP的人进行暴露前预防,以预防HIV传播。Objective To understand the awareness,willingness and objective needs of HIV pre-exposure prevention(PrEP)among men who have sex with men(MSM),and to provide scientific evidence for PrEP promotion.Methods From December 2020 to May 2021,men who had homosexual sex in the last year were recruited to participate in the study through MSM community groups.Demographics information,AIDS-related knowledge and behavior,awareness,intention to use and demand for PrEP were collected by using an online questionnaire system named“Sojump”.The awareness,intention to use,demand and influence factors of HIV PrEP were analyzed.Results A total of 297 MSM were surveyed,including 288 valid questionnaires,with an effective response rate of 96.97%.Of all respondents,61.11%(176/288)MSM who had heard of PrEP,37.15%(107/288)MSM had an objective need for PrEP and 88.64%(156/176)of those who knew PrEP had intention to use it,and 9.66%(17/176)answered all PrEP-related questions correctly.Multivariate logistic regression analysis showed that those who have had more 6 same-sex partners in half a year(aOR=6.553,95%CI:1.777-24.162),those who had used post-exposure prophylaxis in the last year(aOR=9.034,95%CI:2.072-39.393),and those who had a sexually transmitted disease in the last year(aOR=4.606,95%CI:1.005-21.108)had a higher awareness rate of PrEP.Those with a college degree and above(aOR=4.669,95%CI:1.718-12.687)and those with an objective need for PrEP(aOR=5.056,95%CI:1.384-18.474)had a stronger intention to use PrEP.Conclusions The awareness of PrEP among MSM in Beijing is high,but the mastery of specific contents is low,and the objective demand and willingness to use PrEP are high.Therefore,it is necessary to strengthen the promotion of PrEP and to carry out PrEP services in a timely manner to prevent HIV transmission more effective.

关 键 词：人类免疫缺陷病毒 男男性行为者 暴露前预防 需求 

分 类 号：R512.91[医药卫生—内科学]