中药饮片有害微生物负载及鉴定技术研究进展  

Progress on contamination and identification methods of harmful microorganisms in Chinese herbal medicines

作　　者：陈玲 陈维[1] 刘振杰 曾嘉辉 郭伟鹏 吴清平 张菊梅 CHEN Ling;CHEN Wei;LIU Zhenjie;ZENG Jiahui;GUO Weipeng;WU Qingping;ZHANG Jumei(Guangdong Provincial Key Laboratory of Microbial Safety and Health,State Key Laboratory of Applied Microbiology Southern China,Guangdong Detection Center of Microbiology,Institute of Microbiology,Guangdong Academy of Sciences,Guangzhou 510070,Guangdong,China;College of Food Science,South China Agricultural University,Guangzhou 510642,Guangdong,China)

机构地区：[1]广东省科学院微生物研究所广东省微生物分析检测中心华南应用微生物国家重点实验室广东省微生物安全与健康重点实验室,广东广州510070 [2]华南农业大学食品学院,广东广州510642

出　　处：《微生物学通报》2022年第7期2838-2848,共11页Microbiology China

基　　金：国家重点研发计划(2017YFC1600403);广东省科学院实施创新驱动发展能力建设专项(2019GDASYL-0201001)。

摘　　要：中药饮片在种植、采收、加工和储藏等过程中均有可能受到多种微生物的污染,特别是有害微生物如致病细菌、产毒真菌等的存在会影响中药饮片的安全性。本文综述了近年来中药饮片有害微生物的污染情况,比较不同国家药典对中药饮片微生物限度和真菌毒素限量的差异,归纳当前用于不同微生物鉴定方法的适用性,以期为中药饮片质量安全研究工作提供参考。Chinese herbal medicines may be contaminated with microorganisms(pathogenic bacteria and mycotoxigenic fungi)during cultivation,harvesting,processing,and storage,which causes spoilage and consequently affects the safety of herbal medicines.This study summarized the microbial contamination of common herbal medicines in recent years,and compared the limits of microbial and mycotoxin in pharmacopeias of different countries.Moreover,we reviewed the detection and identification methods of microorganisms in herbal medicines to provide a reference for similar research.

关 键 词：中药饮片 有害微生物 污染 微生物鉴定 

分 类 号：R286.0[医药卫生—中药学]