临沂市首起学校聚集性人博卡病毒疫情流行病学调查和分析  

Epidemiological investigation and analysis of the first school-aggregated human bocavirus epidemic in Linyi City

作　　者：李学斌 许艳 LI Xue-bin;XU Yan(Hedong dristrict Center for Disease Control and Prevention,Linyi 276034,Shandong,China)

机构地区：[1]山东省临沂市河东区疾病预防控制中心,山东临沂276034

出　　处：《中国病原生物学杂志》2022年第7期807-809,共3页Journal of Pathogen Biology

摘　　要：目的对一起由人博卡病毒(HBoV)引起的学校聚集性发热疫情进行调查分析,了解疫情性质及发生原因,以便采取控制措施,为类似疾病防控提供经验。方法对2020年5月24日至6月10日发生的一起学校聚集性发热疫情进行现场流行病学调查,并采集咽拭子标本,采用实时荧光定量PCR法对咽拭子进行感染病原体的核酸检测。结果本起疫情共报告发热病例56例,均为学生,年龄13~18岁,罹患率为8.60%。5月24日出现首发病例,6月1日达到发病高峰,6月10报告末例病例。患者临床症状以发热、咳嗽等呼吸道症状为主。采集16例发热病例的咽拭子,实时荧光定量PCR检测6例HBoV核酸阳性。56例患者根据病情采取在校隔离观察、门诊治疗、住院治疗后均恢复健康。疫点学校采取健康监测、宣传教育、通风消毒等防控措施,之后未再发生相应病例。结论该起学校聚集性发热疫情由HBoV引起,提示HBoV引起的呼吸道感染形势严峻,需要制定相应的防控策略,防止该类疫病在学校的发生和流行。Objective To investigate and analyze an epidemic situation of school cluster fever caused by human bocavirus(HBoV),to understand the nature and causes of the epidemic situation,so as to take control measures and provide experience for the prevention and control of similar diseases in the future.Methods On-site epidemiological investigation was conducted on a school cluster fever outbreak from May 24 to June 10,2020.Throat swabs were collected and detected by real-time fluorescence PCR.Results A total of 56 fever cases were reported,all of them were students,ranging from 13 to 18 years old,with an attack rate of 8.60%.The first case appeared on May 24,reached the peak on June 1,and the last case was reported on June 10;Clinical symptoms were mainly respiratory symptoms such as fever and cough;Throat swabs of 16 cases with fever were collected,and 6 cases were positive for HBoV nucleic acid.56 cases recovered after taking school isolation observation,outpatient treatment and hospitalization according to their condition.The epidemic-stricken school has taken preventive measures such as health monitoring,publicity and education,ventilation and disinfection,and no corresponding cases have occurred since then.Conclusion The epidemic situation of fever in school was caused by HBoV,which indicates that the respiratory infection caused by HBoV was severe.Therefore,corresponding researches and control strategies need to be formulated to prevent the occurrence and prevalence of such diseases in schools.

关 键 词：人博卡病毒 聚集性发热疫情 调查分析 

分 类 号：R373[医药卫生—病原生物学]