基于倾向性评分法的藏族非吸烟人群被动吸烟暴露与失眠的关联研究  

Association between passive smoking exposure and insomnia in a Tibetan non-smoking population based on the propensity score

作　　者：何瑞峰[1] 梁逸致 陈林 郭冰 HE Rui-feng;LIANG Yi-zhi;CHEN Lin;GUO Bing(Tibet Center for Disease Control and Prevention,Lasa 850000,China;West China School of Public Health and West China Fourth Hospital,Sichuan University,Chengdu 610044,China;Department of Epidemiology and Health Statistics,West China School of Public Health and West China Fourth Hospital,Sichuan University,Chengdu 610044,China)

机构地区：[1]西藏自治区疾病预防控制中心,拉萨850000 [2]四川大学华西公共卫生学院(华西第四医院),成都610044 [3]四川大学华西公共卫生学院(华西第四医院)流行病与卫生统计学系,成都610044

出　　处：《中华疾病控制杂志》2022年第7期815-819,共5页Chinese Journal of Disease Control & Prevention

基　　金：国家重点研发计划(2017YFC0907302)。

摘　　要：目的描述中国藏族非吸烟人群被动吸烟暴露与失眠症状的分布特征,探究被动吸烟暴露与失眠症状的关联程度。方法基于“西南区域自然人群队列”项目2018年5月―2019年8月在拉萨市调查的7737名藏族居民数据,采用倾向性评分逆概率加权法和边际结构模型分析被动吸烟暴露与失眠症状的关联,并比较该关联在不同年龄、性别、BMI、负性生活事件、社会支持组别之间的差异。结果调查人群中被动吸烟暴露率为22.50%,失眠检出率为33.67%。利用倾向性评分均衡潜在混杂因素后,被动吸烟暴露组发生失眠症状的风险为非被动吸烟暴露组的1.24倍(OR=1.24,95%CI:1.14~1.34);年龄≥50岁(OR=1.25,95%CI:1.01~1.54)、男性(OR=1.60,95%CI:1.17~2.18)、超重(OR=1.24,95%CI:1.05~1.47)、有过1次负性生活事件(OR=1.46,95%CI:1.01~2.10)和中等社会支持(OR=1.46,95%CI:1.12~1.92)人群被动吸烟暴露与失眠有显著关联。结论在藏族非吸烟人群中被动吸烟暴露是失眠的危险因素,应该采取相关降低被动吸烟暴露的干预措施去促进人群睡眠健康。Objective To describe the distribution characteristics of passive smoking exposure and insomnia symptoms in the Tibetan non-smoking population in China.It aims to investigate the extent of association between passive smoking exposure and insomnia symptoms.Methods Based on the data of 7737 Tibetan residents recruited in Lhasa from 2018 to 2019 in the Southwest Regional General Population Cohort Project,the study analyzed the association between passive smoking exposure and insomnia symptoms using the propensity score inverse probability weighting method and marginal structure model.Besides,the association between passive smoking and insomnia was compared across age,gender,BMI,adverse life events,and social support groups.Results The passive smoking exposure rate was 22.50%,and the insomnia detection rate was 33.67%in the survey population.After adjusting for potential confounders,the risk of insomnia symptoms in the passive smoking group was nearly 1.24 times higher than in the non-passive smoking exposed group(OR=1.24,95%CI:1.14-1.34).People who age≥50 years(OR=1.25,95%CI:1.01-1.54),was males(OR=1.60,95%CI:1.17-2.18),overweight(OR=1.24,95%CI:1.05-1.47),have had an adverse life event(OR=1.46,95%CI:1.01-2.10)and moderate social support(OR=1.46,95%CI:1.12-1.92)were suffered more strongly effect of passive smoking exposure on insomnia.Conclusions This study suggests that passive smoking exposure is a risk factor for insomnia in the Tibetan non-smoking population.Interventions regarding reducing passive smoking exposure should be performed to promote sleep health in Tibetans.

关 键 词：藏族人群 被动吸烟 暴露 失眠症状 倾向性评分 

分 类 号：R181[医药卫生—流行病学]