关注慢性乙型肝炎病毒感染“灰区”患者  

Focus on patients with chronic hepatitis B virus infection in the gray zone

作　　者：杨雪芳 胥莹[1] 张帮婷 YANG Xuefang;XU Ying;ZHANG Bangting(Department of Gastroenterology,the Second Affiliated Hospital of Kunming Medical University,Kunming 650101,China)

机构地区：[1]昆明医科大学第二附属医院消化内科,云南昆明650101

出　　处：《胃肠病学和肝病学杂志》2022年第8期938-941,946,共5页Chinese Journal of Gastroenterology and Hepatology

摘　　要：慢性乙型肝炎病毒(hepatitis B virus,HBV)感染的自然病程是复杂的。目前临床大多数研究均基于4个典型感染期,针对“灰区”的研究较少,但经相关研究证实,在就诊患者中,“灰区”患者占据一定比例。本文就“灰区”患者的定义、占比、临床特点以及这部分患者发生肝硬化的风险进行综述,以期更好地完善慢性HBV自然感染分期,并为“灰区”患者的诊断及随访奠定一定基础。The natural course of chronic hepatitis B virus(HBV) infection is complex.At present,most clinical studies are based on 4 typical infection stages,and there are few studies on gray zone.However,it has been confirmed by relevant studies that grey zone patients occupy a certain proportion of patients.In this article,the definition,proportion,clinical characteristics and the risk of cirrhosis in patients with gray zone were reviewed,in order to better improve the natural infection stage of chronic HBV infection,and to lay a certain foundation for the diagnosis and follow-up of patients with gray zone.

关 键 词：乙型肝炎病毒 分期 灰区 定义 丙氨酸转氨酶 肝硬化 

分 类 号：R512.62[医药卫生—内科学]