Comparison of demographic features and laboratory parameters between COVID-19 deceased patients and surviving severe and critically ill cases  

作　　者：Lei Wang Yang Gao Zhao-Jin Zhang Chang-Kun Pan Ying Wang Yu-Cheng Zhu Yan-Peng Qi Feng-JieXie Xue Du Na-Na Li Peng-Fei Chen Chuang-Shi Yue Ji-Han Wu Xin-Tong Wang Yu-Jia Tang Qi-Qi Lai Kai Kang 

机构地区：[1]Department of Critical Care Medicine,The First Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang Province,China [2]Department of Critical Care Medicine,The Sixth Affiliated Hospital of Harbin Medical University,Harbin 150028,Heilongjiang Province,China [3]Department of Critical Care Medicine,The Yichun Forestry Administration Central Hospital,Yichun 153000,Heilongjiang Province,China [4]Department of Critical Care Medicine,The Jiamusi Cancer Hospital,Jiamusi 154007,Heilongjiang Province,China [5]Department of Critical Care Medicine,The First People Hospital of Mudanjiang City,Mudanjiang 157011,Heilongjiang Province,China [6]Department of Critical Care Medicine,The Hongxinglong Hospital of Beidahuang Group,Shuangyashan 155811,Heilongjiang Province,China [7]Department of Cardiology,The Hongxinglong Hospital of Beidahuang Group,Shuangyashan 155811,Heilongjiang Province,China [8]Department of Critical Care Medicine,The Hongqi Hospital Affiliated to Mudanjiang Medical University,Mudanjiang 157011,Heilongjiang Province,China

出　　处：《World Journal of Clinical Cases》2022年第23期8161-8169,共9页世界临床病例杂志

基　　金：Supported by National Natural Science Foundation of China,No.81902000.

摘　　要：BACKGROUND Coronavirus disease 2019(COVID-19) has been far more devastating than expected, showing no signs of slowing down at present. Heilongjiang Province is the most northeastern province of China, and has cold weather for nearly half a year and an annual temperature difference of more than 60℃, which increases the underlying morbidity associated with pulmonary diseases, and thus leads to lung dysfunction. The demographic features and laboratory parameters of COVID-19 deceased patients in Heilongjiang Province, China with such climatic characteristics are still not clearly illustrated.AIM To illustrate the demographic features and laboratory parameters of COVID-19 deceased patients in Heilongjiang Province by comparing with those of surviving severe and critically ill cases.METHODS COVID-19 deceased patients from different hospitals in Heilongjiang Province were included in this retrospective study and compared their characteristics with those of surviving severe and critically ill cases in the COVID-19 treatment center of the First Affiliated Hospital of Harbin Medical University. The surviving patients were divided into severe group and critically ill group according to the Diagnosis and Treatment of New Coronavirus Pneumonia(the seventh edition).Demographic data were collected and recorded upon admission. Laboratory parameters were obtained from the medical records, and then compared among the groups.RESULTS Twelve COVID-19 deceased patients, 27 severe cases and 26 critically ill cases were enrolled in this retrospective study. No differences in age, gender, and number of comorbidities between groups were found. Neutrophil percentage(NEUT%), platelet(PLT), C-reactive protein(CRP), creatine kinase isoenzyme(CK-MB), serum troponin I(TNI) and brain natriuretic peptides(BNP) showed significant differences among the groups(P = 0.020, P = 0.001, P < 0.001, P = 0.001, P < 0.001, P <0.001, respectively). The increase of CRP, D-dimer and NEUT% levels, as well as the decrease of lymphocyte count(LYMPH) and PLT cou

关 键 词：COVID-19 SARS-CoV-2 Deceased patients C-reactive protein D-DIMER Neutrophil percentage Lymphocyte count Platelet 

分 类 号：R563.1[医药卫生—呼吸系统]