Relapsing polychondritis causing breathlessness: Two case reports  

作　　者：Song-Yu Zhai Yu-Hao Zhang Ru-Yan Guo Jie-Wen Hao Shu-Xin Wen 

机构地区：[1]Department of Otorhinolaryngology Head and Neck Surgery,Xi’an Fourth Hospital,Xi’an 710004,Shaanxi Province,China [2]Department of Otorhinolaryngology Head and Neck Surgery,Shanxi Bethune Hospital,Taiyuan 030000,Shanxi Province,China [3]Department of Otorhinolaryngology Head and Neck Surgery,The First People's Hospital of Nanyang,Nanyang 473000,Henan Province,China [4]Department of Otorhinolaryngology Head and Neck Surgery,The Third Clinical College of Shanxi Medical University,Taiyuan 030000,Shanxi Province,China

出　　处：《World Journal of Clinical Cases》2022年第23期8360-8366,共7页世界临床病例杂志

摘　　要：BACKGROUND Relapsing polychondritis is a rare multisystem autoimmune disease that mainly involves systemic cartilage and proteoglycan-rich tissues.If the larynx and trachea are involved,the patient’s condition deteriorates rapidly.When relapsing polychondritis becomes more advanced,the airways collapse and treatment is difficult,rendering a poor prognosis.Therefore,the diagnosis method,treatment strategy and prognosis of relapsing polychondritis with larynx and trachea involvement need to be elucidated to improve clinicians’awareness of the disease.CASE SUMMARY A man and a woman were admitted because of breathlessness.Relapsing polychondritis was diagnosed after a series of accessory examinations.They were both treated with glucocorticoids and immunosuppressants,and underwent tracheotomy as their breathing difficulties could not be relieved by the medication.CONCLUSION The two cases highlight the importance of the timely diagnosis,full evaluation and initiating individualized treatment of relapsing polychondritis with larynx and trachea involvement.Laryngoscopy,bronchoscopy and pathological examination are helpful in diagnosis of this disease.

关 键 词：Relapsing polychondritis LARYNX TRACHEA Case report 

分 类 号：R593.2[医药卫生—内科学]