Catheter-based renal sympathetic nerve denervation on hypertension management outcomes  

作　　者：Som P Singh Kevin J Varghese Fahad M Qureshi Macy C Anderson John Foxworth Mark M Knuepfer 

机构地区：[1]Department of Internal Medicine,University of Missouri Kansas City School of Medicine,Kansas City,MO 64106,United States [2]Department of Pharmacological and Physiological Science,Saint Louis University School of Medicine,Saint Louis,MO 63104,United States

出　　处：《World Journal of Radiology》2022年第7期238-248,共11页世界放射学杂志（英文版）（电子版）

摘　　要：BACKGROUND Renal sympathetic denervation(RSD)provides a minimally invasive interventional treatment modality for patients with resistant hypertension.However,the post-operative outcomes remain a key area of investigation since its earliest clinical trials.AIM To evaluate patient outcomes after RSD intervention among peer-reviewed patient cases.METHODS A systematic review of literature on MEDLINE,Google Scholar,and the Cochrane Database of Systematic Reviews for RSD case studies to assess post-operative hypertension readings and medical management.RESULTS Among 51 RSD cases,the post-operative RSD patients report an apparent reduction with a mean number of 3.1 antihypertensive medications.The mean systolic arterial blood pressure 1 year following RSD was 136.0 mmHg(95%CI:118.7-153.3).CONCLUSION The apparent improvements in office systolic blood pressure after 12 month postoperative RSD can support the therapeutic potential of this intervention for blood pressure reduction.Additional studies which utilized a uniform methodology for blood pressure measurement can further support the findings of this systematic review.

关 键 词：Renal denervation HYPERTENSION Systematic review Interventional radiology OUTCOMES 

分 类 号：R544.1[医药卫生—心血管疾病]