High-flow nasal cannula oxygen therapy during anesthesia recovery for older orthopedic surgery patients: A prospective randomized controlled trial  

作　　者：Xiao-Na Li Cheng-Cheng Zhou Zi-Qiang Lin Bin Jia Xiang-Yu Li Gao-Feng Zhao Fei Ye 

机构地区：[1]Second Clinical Medical College,Guangzhou University of Chinese Medicine,Guangzhou 510000,Guangdong Province,China [2]Department of Anaesthesiology,Guangdong Provincial Hospital of Chinese Medicine(The Second Affiliated Hospital of Guangzhou University of Chinese Medicine),Guangzhou 510000,Guangdong Province,China

出　　处：《World Journal of Clinical Cases》2022年第24期8615-8624,共10页世界临床病例杂志

摘　　要：BACKGROUND Hypoxemia is a common complication in older patients during postoperative recovery and can cause pulmonary complications.Therefore,reducing the incidence of postoperative hypoxemia is a clinical concern.AIM To investigate the clinical efficacy of high-flow nasal cannula oxygen(HFNCO)in the resuscitation period of older orthopedic patients.METHODS In this prospective randomized controlled trial,60 older patients who underwent orthopedic surgery under general anesthesia were randomly divided into two groups:those who used conventional face mask and those who used HFNCO.All patients were treated with 60%oxygen for 1 h after extubation.Patients in the conventional face mask group were treated with a combination of air(2 L)and oxygen(2 L)using a traditional mask,whereas those in the HFNCO group were treated with HFNCO at a constant temperature of 34℃ and flow rate of 40 L/min.We assessed the effectiveness of oxygen therapy by monitoring the patients’arterial blood gas,peripheral oxygen saturation,and postoperative complications.RESULTS The characteristics of the patients were comparable between the groups.One hour after extubation,patients in HFNCO group had a significantly higher arterial partial pressure of oxygen(paO_(2))than that of patients in conventional face mask group(P<0.001).At extubation and 1 h after extubation,patients in both groups showed a significantly higher arterial partial pressure of carbon dioxide(paCO_(2))than the baseline levels(P<0.001).There were no differences in the saturation of peripheral oxygen,paO_(2),and paCO_(2) between the groups before anesthesia and before extubation(P>0.05).There were statistically significant differences in paO_(2) between the two groups before anesthesia and 1 h after extubation and immediately after extubation and 1 h after extubation(P<0.001).However,there were no significant differences in the oxygen tolerance score before leaving the room,airway humidification,and pulmonary complications 3 d after surgery between the two groups(P>0.05).CONCLU

关 键 词：Anesthesia recovery High flow nasal cannula oxygen HYPOXEMIA Older patients Orthopedic surgery Pulmonary complications 

分 类 号：R614[医药卫生—麻醉学]