Cardiac stromal cells on stage:From dull filler to specialized actors  

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作  者:VITTORIO PICCHIO FRANCESCA PAGANO ISOTTA CHIMENTI 

机构地区:[1]Department of Medical Surgical Sciences and Biotechnologies,Sapienza University,Latina,04100,Italy [2]Institute of Biochemistry and Cell Biology,National Council of Research(IBBC-CNR),Monterotondo,00015,Italy [3]Mediterranea Cardiocentro,Napoli,80122,Italy

出  处:《BIOCELL》2022年第8期1875-1877,共3页生物细胞(英文)

基  金:IC is supported by Grant#RG11916B85CDBF76 from Sapienza University;VP is supported by Grant#AR120172B8B543B3 from Sapienza University.FP is supported by Grant#A0375-2020-36621 from Regione Lazio(POR-FESR 2014-2021).

摘  要:Cardiac stromal cells have faced through the years a significant evolution in their definitions concerning their phenotypes,markers,and functions.They are surging to key roles in physiopathology,becoming important targets to be exploited for cardiac repair.In this perspective,we briefly discuss their role in novel therapeutic strategies for enhancing cardiac repair and regeneration.

关 键 词:Cardiac fibroblasts Cardiac stroma Cardiac repair Cardiac remodeling 

分 类 号:R54[医药卫生—心血管疾病]

 

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