质子放射治疗参考剂量研究进展概述  

Overview of the Research Progress of Reference Dosimetry in Proton Radiotherapy

作　　者：齐雅平 霍万里 金孙均[1] 黄骥[1] 王志鹏[1] 张健[1] 王坤[1] QI Yaping;HUO Wanli;JIN Sunjun;HUANG Ji;WANG Zhipeng;ZHANG Jian;WANG Kun(National Institute of Metrology,Beijing 100029,China;China Jiliang University,Hangzhou 310018,China)

机构地区：[1]中国计量科学研究院,北京100029 [2]中国计量大学,杭州310018

出　　处：《计量科学与技术》2022年第6期38-44,共7页Metrology Science and Technology

基　　金：国家重点研发计划(2021YFF0603600);中国计量科学研究院重点领域基本业务费(AKYZD1908);浙江省自然基金(LQ21A050003);安徽省重点研发计划(202104h04020038)。

摘　　要：质子放射治疗因质子在深度剂量上具有布拉格峰特性而逐渐成为一种精准放疗技术。本文介绍了三种质子束参考剂量测量方法,总结了其局限性,并借助蒙特卡洛模拟方法对测量方法的修正项及改进方法进行了讨论,最后概述了微剂量测量的最新进展,为国内研究质子束水吸收剂量测量工作提供了参考。Proton radiotherapy has gradually become a precision radiotherapy technique owing to the characteristic of Bragg Peak on the depth-dose distribution. This paper introduces the details of three proton beam reference dosimetry methods as well as the corresponding limitations in clinical proton modalities. Further discussions on the correction terms and improvement methods of measurements combined with Monte Carlo techniques have been proposed. Finally, the stateof-the-art determination on microdosimetry of proton beams has been summarized, which provides a reference for research on proton beam water absorption dose measurement.

关 键 词：质子放射治疗 参考剂量 量热法 电离室 微剂量 

分 类 号：R815[医药卫生—放射医学]