高血压增加急性心肌梗死患者冠状动脉血管多支病变的风险  

HYPERTENSION INCREASES RISK OF MULTI-CORONARY ARTERIES STENOSIS IN ACUTE MYOCARDIAL INFARCTION PATIENTS

作　　者：于双平[1] 薛然 侯亦楠 邢爱君[1] 郭丽君 陈娇娜 梁欣[1] YU Shuangping;XUE Ran;HOU Yinan;XING Aijun;GUO Lijun;CHEN Jiaona;LIANG Xin(Department of Cardiology,Kailuan General Hospital,Tangshan 063000,China)

机构地区：[1]开滦总医院,063000 [2]开滦林西医院

出　　处：《中国煤炭工业医学杂志》2022年第3期329-332,共4页Chinese Journal of Coal Industry Medicine

基　　金：河北省医学科学研究课题计划(编号:20210929)。

摘　　要：目的 探讨高血压对急性心肌梗死患者冠脉血管多支病变的影响。方法 2019年1—12月于该院因急性心肌梗死且急诊经皮冠脉介入诊疗的178例患者为研究对象,收集患者的病历资料进行了回顾性分析。根据高血压病史将入选对象分为高血压组(113例)和非高血压组(65例),比较二组一般临床资料、冠状动脉病变支数,并对可能影响冠状动脉多支病变的危险因素进行分析。结果 与非高血压组比较,高血压组患者冠状动脉发生三支病变的占比高(58.4%vs.36.9%,χ^(2)=9.412),组间比较差异有统计学意义(P=0.009);将可能影响冠状动脉血管多支病变的危险因素进行单、多因素Logistic分析显示,高血压增加急性心肌梗死患者冠状动脉血管多支病变的风险,OR值分别为2.399(95%CI:1.281~4.493)、2.045(95%CI:1.066~3.924),年龄每增加1岁急性心肌梗死患者冠状动脉血管多支病变的风险比为1.040(95%CI:1.009~1.072)。结论 高血压是急性心肌梗死患者冠状动脉血管多支病变的独立危险因素。Objective To investigate the influence of hypertension on multi-coronary arteries stenosis in acute myocardial infarction(AMI) patients.Methods In this study,one hundred sventy-eight AMI patients that had received emergncy percutaneous coronary intervention treatment during Jan 2019 to Dec 2019 in the KaiLuan Hospital are selected as study subjects and their inpatient medical records data are analyzed.According to the history of hypertension,subjects are divided as hypertension group(n=113) and control group(n=65).The general clinical data,the number of stenosed coronary artery and the risk factors of multi-coronary arteries stenosis are analyzed with statistical methods in this study.Results The proportion of three coronary arteries stenosis in hypertension group is significantly higher than control group(58.4% versus 36.9%,χ^(2)=9.412,P=0.009).The risk factors of multi-coronary arteries stenosis are analyzed by univariate and multivariate logistic models in this study.The results show that hypertension increases the risk of multi-coronary arteries stenosis in AMI patients,the OR value is 2.399(95%CI:1.281~4.493)in univariate logistic model and after adjusted by age the OR value is 2.045(95%CI:1.066~3.924)in multivariate logistic model.Along with 1-year increasing in age,the risk of multi-coronary arteries stenosis in AMI patients increases 1.04 times(RR=1.040,95%CI:1.009~1.072).Conclusion Hypertension and age are independent risk factors of multi-coronary arteries stenosis in AMI patients.

关 键 词：急性心肌梗死 高血压 多支病变 

分 类 号：R587[医药卫生—内分泌]